+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Effect of periodic rest on hearing loss and cochlear damage following exposure to noise



Effect of periodic rest on hearing loss and cochlear damage following exposure to noise



Journal of the Acoustical Society of America 82(4): 1253-1264



Changes in hearing sensitivity and cochlear damage were determined in two groups of chinchillas exposed to an octave band of noise (OBN) centered at 0.5 kHz, 95 db SPL on two different schedules; 6 h per day for 36 days, or 15 min/h for 144 days. Hearing sensitivity was measured behaviorally at 1/4-oct frequency intervals from 0.125 to 16.0 kHz before, during, and for a period of 1 to 2 months after the exposure, at which time the animals' cochleas were fixed and prepared for microscopic examination. Cochlear damage was determined by counts of missing sensory cells. Both exposures produced an initial shift of thresholds of 35-45 dB; however, after a few days of exposure, thresholds began to decline and eventually recovered to within 10-15 dB of original baseline values even though the exposure continued. Measures of recovery made after completion of the exposures indicated minimal permanent threshold shifts in all animals. The behavioral and anatomical data indicated that these intermittent exposures produced less temporary and permanent hearing loss and less cochlear damage than continuous exposures of equal energy.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 005260003

Download citation: RISBibTeXText

PMID: 3680782

DOI: 10.1121/1.395261


Related references

The effect of an age-related hearing loss gene (Ahl) on noise-induced hearing loss and cochlear damage from low-frequency noise. HearingResearch204(1-2):90, 2005

Acrylonitrile potentiates hearing loss and cochlear damage induced by moderate noise exposure in rats. Toxicology and Applied Pharmacology 204(1): 46-56, 2005

Normal structure of the organ of Corti and the effect of noise-induced cochlear damage. In: Sensorineural hearing loss. Ciba Foundation Symposium 1970: 127-156, 1970

Combined use of glucose and rest period between noise exposure to reduce noise--induced hearing loss. Zhonghua Yu Fang Yi Xue Za Zhi 26(2): 67-69, 1992

Hidden Hearing Loss? No Effect of Common Recreational Noise Exposure on Cochlear Nerve Response Amplitude in Humans. Frontiers in Neuroscience 11: 465, 2017

Hearing loss and cochlear pathology in monkeys after noise exposure. Acta Oto-Laryngologica 81(3-4): 337-343, 1976

Hidden hearing loss-damage to hearing processing even with low-threshold noise exposure?. Hno 67(6): 417-424, 2019

Growth of hearing loss and cochlear lesion with increasing duration of noise exposure. Hamernik, R P , D Henderson And R Salvi (Ed ) New Perspectives on Noise-Induced Hearing Loss; Meeting, Cazenovia, N Y , Usa, June 15-18, 1980 Xvi+534p Raven Press: New York, N Y , Usa Illus P283-302, 1982

Hearing loss and cochlear pathology in the monkey (Macaca) following exposure to high levels of noise. Archives of Oto-Rhino-Laryngology 220(1-2): 47-72, 1978

Chronic lead exposure induces cochlear oxidative stress and potentiates noise-induced hearing loss. Toxicology Letters 292: 175-180, 2018

The effects of a hearing education program on recreational noise exposure, attitudes and beliefs toward noise, hearing loss, and hearing protector devices in young adults. Noise and Health 17(78): 253-262, 2015

Noise-induced hearing loss (NIHL) as a target of oxidative stress-mediated damage: cochlear and cortical responses after an increase in antioxidant defense. Journal of Neuroscience 33(9): 4011-4023, 2013

Effect of environmental risk factors in occupational noise exposure to noise-induced hearing loss. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 26(12): 721-724, 2008

Hearing loss observed in guinea pigs after exposure to pink noise of 100 dB(A) for 12 weeks (auditory damage and recovery). Agressologie: Revue Internationale de Physio-Biologie et de Pharmacologie Appliquees Aux Effets de l'Agression 19(4): 257-267, 1978

Noise-induced cochlear hypoxia is intensity dependent, correlates with hearing loss and precedes reduction of cochlear blood flow. Audiology and Neuro-Otology 1(3): 148-160, 1996