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Effect of prior immunization and subsequent challenge with rabies virus in mice

, : Effect of prior immunization and subsequent challenge with rabies virus in mice. Indian Journal of Medical Research 71(JUNE): 833-839

Experiments were carried out to analyze the effect of prior vaccination on biochemical changes in mice given fixed rabies virus intracerebrally. The parameters studied included blood sugar, body temperature and brain monoamines and free amino acids. Mice which developed the disease, irrespective of vaccination history, showed identical changes in all the parameters studied. Mice which survived the infection all had normal body temperature but some showed abnormal blood sugar, brain monoamine and free amino acid values.

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