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Effect of progesterone on the testis thumb pad and pars distalis of the skipper frog rana cyanophlyctis

, : Effect of progesterone on the testis thumb pad and pars distalis of the skipper frog rana cyanophlyctis. Proceedings of the Indian National Science Academy Part B Biological Sciences 49(6): 620-627

Effects of i.m. injection (10 .mu.g and 100 .mu.g progesterone, on alternate day for 14 days) on the testis, thumb pad and pars distalis of pituitary gland in R. cyanophlyctis were studied. Progesterone treatment at both the dose levels resulted in the arrest of spermatogenesis, significant decrease in the relative weight of testes, tubule diameter, Leydig cell nuclear diameter, .DELTA.5-3.beta.-hydroxysteroid dehydrogenase and glucose-6-phosphate dehydrogenase activity, height of thumb pad epidermis and glandular epithelium, and a significant increase (P < 0.05) in length and accumulation of granules in B2 cells. Progesterone apparently has antigonadal effect at the given dose levels.

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