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Effect of propranolol on the ventilatory response to hypercapnia in man


, : Effect of propranolol on the ventilatory response to hypercapnia in man. Clinical Science 57(5): 465-468

The effect of a single oral dose of propranolol on the ventilatory response to hypercapnia was studied in 5 healthy subjects. Propranolol produced a small but significant reduction in the slope of the ventilation/end-tidal PCO2 [CO2 partial pressure] regression line. Propranolol did not significantly change vital capacity or forced expiratory volume in 1 s.

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Accession: 005264689

PMID: 519956

DOI: 10.1042/cs0570465

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Related references

Patrick, J.M.; Tutty, J.; Pearson, S.B., 1978: Propranolol and the ventilatory response to hypoxia and hypercapnia in normal man. The effect on respiration of a single dose of propranolol was studied in normal subjects. The degree of .beta.-adrenoreceptor blockade was assessed in terms of the impaired heart-rate response to progressive exercise and the plasma propranolol con...

Folgering, H.; Braakhekke, J., 1980: Ventilatory response to hypercapnia in normal subjects after propranolol, metoprolol and oxprenolol. Steady state ventilatory response curves to CO2 were taken in 8 normal subjects in control situations and taking clinical doses of propranolol, oxprenolol and metoprolol in a double-blind crossover design. Furthermore, the expiratory peak flow was...

Campbell S.C.; Cobb R.B.; Lauver G.L., 1980: Depression of the ventilatory and occlusion pressure response to hypercapnia with chronic oral administration of propranolol. American Review of Respiratory Disease 121(4 SUPPL): 323

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Berkman, R.A.; Meyer, K.T.; Rosenberg, A.G.; Dutton, R.E., 1978: Depressant effect of ammonia on the ventilatory response to hypoxia and hypercapnia. Advances in Experimental Medicine and Biology 99: 219-230