EurekaMag.com logo
+ Site Statistics
References:
48,252,460
Abstracts:
22,798,453
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Effect of prostaglandin f 2 alpha on ovulation and collagenolytic activities in the rabbit treated by indomethacin


, : Effect of prostaglandin f 2 alpha on ovulation and collagenolytic activities in the rabbit treated by indomethacin. Acta Obstetrica et Gynaecologica Japonica (Japanese Edition) 38(1): 81-87

To clarify a regulatory role of prostaglandins in collagenolytic enzyme activities of the follicular wall at ovulation, we studied whether the ovulation-blocking effect of indomethacin (IM) on hCG-stimulated rabbits could be reversed by an intravenous infusion of PGF2.alpha. The activities of BANA hydrolase and DNP peptidase were also measured by using synthetic substrates N-benzoyl-DL-arginine-2-naphthylamide HC1 (BANA) and DNP-Pro-Gln-Gly-Ile-Ala-Gly-Gln-D-Arg-OH (DNP peptide), respectively, every hour during the specific preovulatory period. The ovulation-blocking effect of IM(4mg/kg) was reversed by an intravenous infusion of PGF2.alpha. (1.5mg/kg) starting at 3 hr after the hCG injection. In the control rabbits treated with hCG(100 iu) alone, these enzymatic activities were increased toward ovulation with the peak level 7-9 hr after a hCG injection and decreased significantly at 10 hr. The preovulatory increase in these enzymatic activities disappeared following the ovulation-blocking doses of indomethacin. By the addtion of the PGF2.alpha. infusion, the IM-induced changes in BANA hydrolase and DNP peptidase activities were returned close to the control. It is suggested that the preovulatory increased in BANA hydrolase and DNP peptidase are mandatory for ovulation and PGF2.alpha. facilitates ovulation through its regulatory action on these enzymes.

(PDF 0-2 workdays service)

Order PDF Full Text

Close
Close

Click here to order any other PDF Full Text


Accession: 005264909

PDF Full Text: Submit


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Other references

De Sarasola M.A.R.; Sarasola A.A., 1968: Control of grape d anthracnose with chemo therapeutants applied to the soil elsinoe ampelina. Revista de Investigaciones Agropecuarias Serie 5 Patologia Vegetal 5(3): 19-29

Seago, J. L.; Wolniak, S. M., 1976: Cortical ontogeny in roots part 1 zea mays. Serial growth stages of young Z. mays primary roots were analyzed for patterns of ground meristem ontogeny. The number of cell layers in the cortex decreases from approximately 15 to 11 during early root growth. The cortex arises mostly by pericli...

Piazza, R; Venturi, G., 1974: Comparative trials between bush redpeppers cultivars (Capsi sum annuum L.). Rivista di agronomia: 8 (1) 67-75

Godfrey Paul J. (investigator), 1981: Oceanic overwash and its ecological implications on the outer banks of North Carolina (Calo-N-1 and 2). 58: 321-333 1981

Fung, K. P.; Lam, W. P.; Choy, Y. M.; Lee, C. Y., 1996: Effect of methotrexate on the intracellular phosphoribosyl pyrophosphate level and glucose transport of Ehrlich ascites tumor cells in vitro. Methotrexate (MTX) suppressed the growth of Ehrlich ascites tumor (EAT) cells in vitro. The intracellular level of phosphoribosyl 5-pyrophosphate (PRPP) of EAT cells increased in a dose-dependent manner in response to MTX treatment. At the same ti...

Hyacinth I. Hyacinth; Beatrice E. Gee; Thomas V. Adamkiewicz; Robert J. Adams; Abdullah Kutlar; Jonathan K. Stiles; Jacqueline M. Hibbert, 2012: Plasma BDNF and PDGF-AA levels are associated with high TCD velocity and stroke in children with sickle cell anemia. Sickle cell anemia (SCA) associated cerebrovascular disease includes vascular remodeling, abnormal cerebral blood flow (CBF) and infarction. We studied the relationships between plasma brain derived neurotropic factor (BDNF), platelet derived grow...

Mazzuoli G.; Minisola S.; Valtorta C.; Antonelli R.; Tabolli S.; Bigi F., 1985: Changes in mineral content and biochemical bone markers at the menopause. Serum alkaline phosphatase activity, serum bone .gamma.-carboxyglutamic acid protein, urinary hydroxyproline and bone mineral content were simultaneously measured in 30 age-matched pre- and postmenopausal women in order to define the temporal rela...

Anonymous, 2011: Metal Al, Mn, Pb and Zn soils extractable reagents for available fraction assessment Comparison using plants, and dry and moist soils from the Bracal abandoned lead mine area, Portugal. Eleven composite soil samples, developed either on schist materials or fine heterogeneous waste materials and coarse metallurgical slags, were collected in the Bra al (Portugal) abandoned lead mine. Plants growing in each sampling area were identi...

Combe Michel, 1971: Organization of the studies on Moroccan water resources. History, division of the water resources administration, general estimates of resources.

Bogard Donald D.; Garrison Daniel H., 1998: Composition of Martian noble gases trapped in Martian meteorite impact glasses. Abstracts of Papers Submitted to the Lunar and Planetary Science Conference: 998.