+ Translate
+ Most Popular
The pigeon tick (Argas reflexus): its biology, ecology, and epidemiological aspects
Prevalence of hemoglobin abnormalities in Kebili (Tunisian South)
Lipogranuloma: a preventable complication of dacryocystorhinostomy
Value of basal plasma cortisol assays in the assessment of pituitary-adrenal insufficiency
Bees from the Belgian Congo. The acraensis group of Anthophora
Placing gingival retraction cord
Total serum IgE, allergy skin testing, and the radioallergosorbent test for the diagnosis of allergy in asthmatic children
Acariens plumicoles Analgesoidea parasites des oiseaux du Maroc
Injuries of terminal phalanges of the fingers in children
Biology of flowering and nectar production in pear (Pyrus communis)
Das Reliktvorkommen der Aspisviper (Vipera aspis L.) im Schwarzwald
Hydrological modelling of drained blanket peatland
Pathologic morphology and clinical significance of the anomalous origin of the left circumflex coronary artery from the right coronary artery. General review and autopsy analysis of 30 cases
Cyto genetic analyses of lymphocyte cultures after exposure to calcium cyclamate
Axelrodia riesei, a new characoid fish from Upper Rio Meta in Colombia With remarks concerning the genus Axelrodia and description of a similar, sympatric, Hyphessobrycon-species
Favorable evolution of a case of tuberculosis of pancreas under antibiotic action
RIFM fragrance ingredient safety assessment, Valencene, CAS Registry Number 4630-07-3
Parenteral microemulsions: an overview
Temperate pasture: management for grazing and conservation
Evaluation of a new coprocessed compound based on lactose and maize starch for tablet formulation
Thermal expansion and cracking of three confined water-saturated igneous rocks to 800C
Revision of the genera of the tribe Stigmoderini (Coleoptera: Buprestidae) a discussion of phylogenetic relationships
Anal tuberculosis. Report of a case
Gastric tuberculosis in the past and present
Adaptive responses of the cardiovascular system to prolonged spaceflight conditions: assessment with Holter monitoring

Effect of therapy on blood serum lipids and prolonged fenofibrate lipoproteins in patients with hypercholesterolemia and hypertriglyceridemia

Effect of therapy on blood serum lipids and prolonged fenofibrate lipoproteins in patients with hypercholesterolemia and hypertriglyceridemia

Polski Tygodnik Lekarski 41(51-52): 1633-1637

ISSN/ISBN: 0032-3756

An effect of a 3-year treatment with fenofibrate was evaluated in 35 patients with hypertrigliceridemia. Serum total cholesterol, LDL + VLDL or LDL, HDL and ratio LDL + VLDL/HDL or LDL/HDL were determined. The same parameters were determined in 20 patients with heterozygotic inherited hypercholesterolemia treated for 2 years. A significant decrease in total cholesterol concentration, LDL cholesterol or LDL + VLDL, LDL + VLDL/HDL or LDL/HDL ratio; and in triglycerides was seen in all examined patients. A significant increase in HDL-cholesterol was observed in patients with hypertriglyceridemia while it remained unchanged in hypercholesterolemia. The obtained results suggest that fenofibrate exerts hypolipemic action during chronic administration. The drug may be an alternative therapy to cholestyramine in some cases in monogenic forms of hypercholesterolemia due to its efficacy.

Please choose payment method:

(PDF emailed within 1 workday: $29.90)

Accession: 005278052

Download citation: RISBibTeXText

Related references

Effect of long-term treatment with fenofibrate on serum lipids and lipoproteins in patients with hypercholesterolemia and hypertriglyceridemia. Polski Tygodnik Lekarski 41(51-52): 1633-1637, 1986

The effect of ezetimibe on serum lipids and lipoproteins in patients with homozygous familial hypercholesterolemia undergoing LDL-apheresis therapy. Atherosclerosis 186(1): 126-131, 2006

The effect of atorvastatin on serum lipids and lipoproteins in patients with homozyous familial hypercholesterolemia undergoing LDL-apheresis therapy. Atherosclerosis 153(1): 89-98, 2000

Effect of fenofibrate on serum lipoproteins in subjects with familial hypercholesterolemia and combined hyperlipidemia. Atherosclerosis 53(3): 321-325, 1984

Low-dose effect of simvastatin (MK-733) on serum lipids, lipoproteins, and apolipoproteins in patients with hypercholesterolemia. Clinical Therapeutics 11(2): 247-257, 1989

Effects of fenofibrate on lipids, lipoproteins, and apolipoproteins in 33 subjects with primary hypercholesterolemia. Atherosclerosis 63(1): 57-64, 1987

Long term effect of cs 514 3 hydroxy 3 methylglutaryl coenzyme a reductase inhibitor on serum lipids lipoproteins and apolipoproteins in patients with hypercholesterolemia. Current Therapeutic Research 42(3): 491-500, 1987

Effects of free omega-3 carboxylic acids and fenofibrate on liver steatosis and serum lipoproteins in overweight patients with hypertriglyceridemia and non-alcoholic fatty liver disease (NAFLD). Atherosclerosis 263: E260-E260, 2018

Effects of simvastatin and fenofibrate on serum lipoproteins and apolipoproteins in primary hypercholesterolaemia. European Journal of Clinical Pharmacology 37(2): 199-203, 1989

Effect of fenofibrate on serum nitric oxide levels in patients with hypertriglyceridemia. Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University 28(7): 931-936, 2019

Diet and hypertriglyceridemia: influence of dietary modifications on plasma lipids, lipoproteins and apoproteins in patients with primary hypertriglyceridemia. Medicina Clinica 98(17): 646-650, 1992

Marked differences in the response of serum lipoproteins to fenofibrate in women and men with primary hypercholesterolemia. Atherosclerosis 109(1-2): 325-326, 1994

Effect of prolonged fasting on serum lipids and serum lipoproteins in obese men. Hoppe-Seyler'sZeitschriftf├╝rPhysiologischeChemie355(10):1184, 1974

Single-strand conformation polymorphism analysis on the -sarcoglycan gene in Japanese patients with hypertrophic cardiomyopathy. The American Journal of Cardiology 85(11): 1315-1318, 2000

Effect of a rapeseed oil substituting diet on serum lipids and lipoproteins in children and adolescents with familial hypercholesterolemia. Journal of the American College of Nutrition 21(2): 103-108, 2002