Effects of maternally administered sulfur 35 on the pre natal and post natal mortality and development in mice
Reddy, K.S.; Reddy, P.P.; Reddi, O.S.
Indian Journal of Animal Sciences 48(1): 52-54
ISSN/ISBN: 0367-8318 Accession: 005313552
Pregnant CBA mice were injected i.p. with 20 .mu.Ci of 35S on day 10.5 of gestation and allowed to go to term. No mortality was observed in treated animals. However, a slight reduction in the number of fertile matings was noted in 35S group. But the reduction was statistically insignificant. A significant decrease in litter size was noted in 35S-treated group. While the litter size was 7.5/.female. in the control, it was 5.9/.female. in 35-group. The reduced litter size may be due to 35S-induced prenatal mortality. A further reduction in litter size was noted at weaning. This reduction was due to a significant increase in the neo- and postnatal mortality of F1 progeny in the treated group. There was no effect of 35S on the sex ratio and body weight of F1 progeny.