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Effects of midazolam in conjunction with alcohol on iconic memory and free recall

Effects of midazolam in conjunction with alcohol on iconic memory and free recall

Neuropsychobiology 9(4): 230-234

The effects of midazolam 15 mg and alcohol 0.5 g/kg on short-term storage in the visual system (iconic memory) and free recall of a word list were investigated in 8 normal volunteers. Acute doses of midazolam, alcohol and midazolam in combination with alcohol all decreased iconic memory; only midazolam and midazolam + alcohol impaired immediate recall. Anterograde amnesia was observed following treatment with midazolam and midazolam in conjuction with alcohol. A potentiation of the effects of midazolam, on aspects of human memory by the co-administration of small doses of alcohol was suggested.

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