Effects of nitrilo tri acetic acid on apparent absorption and duodenal flow of manganese iron zinc and copper in sheep
Ivan, M.; Ihnat, M.; Hidiroglou, M.
Canadian Journal of Animal Science 59(2): 273-282
1979
ISSN/ISBN: 0008-3984 Accession: 005316290
A Latin square design was used with 4 sheep, each equipped with a rumen fistula and re-entrant cannula in the proximal duodenum. The 4 treatments were intraruminal dosings with different amounts (0, 450, 900 and 1800 mg/day) of nitrilotriacetic acid (NTA) 1 [a chelating agent]. The sheep were fed a pelleted diet with excessive concentrations of Mn, Fe, Zn and Cu. Fecal excretion of Fe and Zn increased and apparent absorption decreased with increasing dose of NTA. Only the differences between means for Zn were statistically significant. Fecal excretion and apparent absorption of Mn and Cu were not affected by NTA. Flow of soluble Fe through the duodenum increased with increasing dose of NTA. There was no effect of NTA on concentrations of Mn, Fe, Zn and Cu in the rumen bacteria or on microbial activity in the rumen as measured by the concentration of volatile fatty acids in the rumen and by flow of N into the small intestine.