+ Most Popular
Cunninghamia lanceolata plantations in China
Mammalian lairs in paleo ecological studies and palynology
Studies on technological possibilities in utilization of anhydrous milk fat for production of recombined butter-like products
Should right-sided fibroelastomas be operated upon?
Large esophageal lipoma
Apoptosis in the mammalian thymus during normal histogenesis and under various in vitro and in vivo experimental conditions
Poissons characoides nouveaux ou non signales de l'Ilha do Bananal, Bresil
Desensitizing efficacy of Colgate Sensitive Maximum Strength and Fresh Mint Sensodyne dentifrices
Administration of fluid by subcutaneous infusion: revival of a forgotten method
Tundra mosquito control - an impossible dream?
Schizophrenia for primary care providers: how to contribute to the care of a vulnerable patient population
Geochemical pattern analysis; method of describing the Southeastern limestone regional aquifer system
Incidence of low birth weights in a hospital of Mexico City
Graded management intensity of grassland systems for enhancing floristic diversity
Microbiology and biochemistry of cheese and fermented milk
The ember tetra: a new pygmy characid tetra from the Rio das Mortes, Brazil, Hyphessobrycon amandae sp. n. (Pisces, Characoidei)
Risk factors of contrast-induced nephropathy in patients after coronary artery intervention
Renovation of onsite domestic wastewater in a poorly drained soil
Observations of the propagation velocity and formation mechanism of burst fractures caused by gunshot
Systolic blood pressure in a population of infants in the first year of life: the Brompton study
Haematological studies in rats fed with metanil yellow
Studies on pasteurellosis. I. A new species of Pasteurella encountered in chronic fowl cholera
Dormancy breaking and germination of Acacia salicina Lindl. seeds
therapy of lupus nephritis. a two-year prospective study

Effects of scopolamine on spontaneous alternation and shuttle avoidance in rats exposed to alcohol in utero

Effects of scopolamine on spontaneous alternation and shuttle avoidance in rats exposed to alcohol in utero

Alcohol 2(4): 575-579

ISSN/ISBN: 0741-8329

PMID: 4026982

DOI: 10.1016/0741-8329(85)90083-7

The behavioral effects of the anticholinergic scopolamine were examined in rats exposed to alcohol prenatally. Pregnant Long-Evans rats received isocaloric liquid diets containing either 35% or 0% ethanol-derived calories on days 6-20 of gestation. A pair-feeding procedure was used, and a lab chow control group was also included. In experiment 1, adult offspring were tested on a spontaneous alternation task following 1 mg/kg scopolamine or saline. Independent of prenatal treatment, scopolamine caused an increase in the number of trials to alternate. In experiment 2, offspring were tested on a 2-way shuttle avoidance learning task following a 1 mg/kg injection of scopolamine or methylscopolamine. Alcohol-exposed animals injected with methylscopolamine made fewer avoidances than controls on the 2nd day of testing while treatment with scopolamine enhanced avoidance performance to control levels. Prenatal exposure to alcohol apparently does not interfere with scopolamine-induced changes in the behavior of adult rats.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 005324126

Download citation: RISBibTeXText

Related references

Effects of physostigmine on shuttle avoidance in rats exposed prenatally to ethanol. Alcohol 5(1): 27-31, 1988

Effects of housing density restraint and shock on alcohol consumption in rats exposed to alcohol in utero. Alcoholism Clinical and Experimental Research 5(2): 349, 1981

Effects of chlordiazepoxide-scopolamine combinations on shuttle-box avoidance performance of mice. Archives Internationales de Pharmacodynamie et de Therapie 235(1): 93-102, 1978

Effects of oxiracetam-scopolamine combinations on shuttle-box avoidance acquisition in mice. Archives Internationales de Pharmacodynamie et de Therapie 291: 208-216, 1988

Sexually dimorphic effects of alcohol exposure in utero on neuroendocrine and immune functions in chronic alcohol-exposed adult rats. Molecular and Cellular Neurosciences 4(4): 343-353, 1993

Effects of scopolamine and D-amphetamine on one-way, shuttle and inhibitory avoidance: a diallel analysis in mice. Pharmacology Biochemistry and Behavior 3(6): 1037-1042, 1975

Comparative studies of huperzine A and tacrine on scopolamine-induced amnesia of shuttle-box active avoidance in adult and aged rats. Society for Neuroscience Abstracts 22(1-3): 439, 1996

Effects of 9-THC, LSD-25 and scopolamine on continuous, spontaneous alternation in the Y-maze. Psychopharmacology 32(2): 171-182, 1973

Dissociation of the effects of scopolamine and d-amphetamine on a spontaneous alternation task. Pharmacology Biochemistry and Behavior 5(3): 293-297, 1976

Effects of delta9-THC, LSD-25 and scopolamine on continuous, spontaneous alternation in the Y-maze. Psychopharmacologia 32(2): 171-182, 1973

Effects of scopolamine on spontaneous alternation following free and forced trials. Physiology and Behavior 5(3): 331-334, 1970

Effects of intermittent aerobic training on passive avoidance test (shuttle box) and stress markers in the dorsal hippocampus of wistar rats exposed to administration of homocysteine. Iranian Journal of Psychiatry and Behavioral Sciences 7(1): 37-44, 2013

Effects of tianeptine on spontaneous alternation, simple and concurrent spatial discrimination learning and on alcohol-induced alternation deficits in mice. Behavioural Pharmacology 2(1): 37-46, 1991

Effect of 4-(o-benzylphenoxy)-N-methylbutylamine hydrochloride (MCI-2016) on the scopolamine-induced deficit of spontaneous alternation behavior in rats. Japanese Journal of Pharmacology 33(4): 775-784, 1983

Effects of scopolamine on shuttle-box avoidance and go-no go discrimination: response-stimulus relationships, pretreatment baselines, and repeated exposure to drug. Psychopharmacologia 13(2): 89-105, 1968