+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Effects of temperature on triiodothyronine plasma levels kinetics and hepatocyte nuclear binding in rainbow trout salmo gairdneri

Effects of temperature on triiodothyronine plasma levels kinetics and hepatocyte nuclear binding in rainbow trout salmo gairdneri

Canadian Journal of Zoology 64(12): 2658-2664

Plasma levels of 3,5,3'-triiodo-L-thyronine (T3), plasma T3 kinetics, and properties of in vivo T3 binding to saturable hepatocyte nuclear sites were studied in fed immature rainbow trout maintained at 12.degree. C and then held for up to 14 d at 5, 11-12, or 19.degree. C. Elevation (19.degree. C) or depression (5.degree. C) of plasma T3 occurred during the first 3 h following abrupt transfer from 11.degree. C, but from 12 h to 7 d, plasma T3 did not differ significantly among the three temperatures. In contrast, the plasma T3 degradation rate increased fourfold from 5 to 19.degree. C largely because of an increased fractional rate of turnover of the plasma T3 pool. Outer-ring deiodination of T3 was negligible at 5 and 12.degree. C and slight at 19.degree. C. Temperature did not influence the proportion of [125I]T3 lost via the enterohepatic route. Uptake of [125I]T3 into the liver and liver nuclear fraction was most rapid at 19.degree. C, intermediate at 12.degree. C, and least rapid at 5.degree. C. Saturable nuclear binding of [125I]T3 occurred at all temperatures. The apparent affinity of T3 for hepatic nuclear sites was similar at 12 and 19.degree. C but lower at 5.degree. C; the apparent site capacity underwent no significant change with temperature. In conclusion, over the range of 5 to 19.degree. C there are marked increases in plasma T3 clearance, rate of T3 uptake from plasma to liver, and rate of T3 uptake by the liver nuclear fraction, but relatively small changes in plasma T3 level, proportion of T3 excreted via the enterohepatic route, and properties of the saturable T3-binding nuclear sites.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 005329100

Download citation: RISBibTeXText

DOI: 10.1139/z86-386

Related references

Effects of temperature on the oxidative and lipolytic capacities of manduca sexta flight muscles. American Zoologist 24(3): 110A, 1984

Effects of temperature on photosynthesis and respiration in hermatypic corals. Marine Biology 43(3): 209-216, 1977

Effects of Diesel engine exhaust on pulmonary alveolar macrophages. Scanning Electron Microscopy 1980(3): 327-338, 1980

Development of search procedures in real life spatial environments. Developmental Psychology 15(5): 530-542, 1979

Development of reagent for cancer diagnosis by urine color reaction (I)-comparative analysis of cancer and non-cancer urine by NMR, HPLC and Gift reagent. Archives of Pharmacal Research 11(2): 134-138, 1988

Effect of acclimation temperature on oxygen transport in the blood of the carp cyprinus carpio. Respiration Physiology 52(2): 165-180, 1983

Changes in pigment composition during aGymnodiniumbloom in the Brahmsarovar tank at Kurukshetra. Proceedings: Plant Sciences 88(5): 407-412, 1979

Effect of rapid stomatal opening in darkness at temperature lethal for plants. 1974

Effects of photoperiod and temperature on ovarian development in the congiopodid fish hypodytes rubripinnis. Journal of the School of Marine Science and Technology Tokai University (18): 265-274, 1984

Temperature-independent morning emergence in lizards of the genus Phn/nosomn. Science 138: 891-892, 1962

Effects of starling excrement in the food of cattle and pigs. Animal Production 38(3): 439-446, 1984

Effect of prolonged-action fenfluramine on weight and blood lipids in obese patiente. Current Medical Research and Opinion 6(S1): 169-179, 1979

Thyroid hormone and hepatic udp glucuronosyl transferase ec activity contrary effects in rat and mouse. Research Communications in Chemical Pathology and Pharmacology 39(3): 445-462, 1983

The effects of cadmium on delta aminolevulinic acid dehydratase activity growth and hemoglobin content in the water flea daphnia magna. Comparative Biochemistry and Physiology C Pharmacology Toxicology and Endocrinology 80(2): 407-410, 1985

Effects of feeding and of chemical stimulation on the oxygen uptake of nassarius reticulatus gastropoda prosobranchia. Journal of the Marine Biological Association of the United Kingdom 58(2): 387-400, 1978