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Effects of the association between di phenyl hydantoin and amphetamine or nicotine in rats submitted to a 2 way active avoidance conditioning



Effects of the association between di phenyl hydantoin and amphetamine or nicotine in rats submitted to a 2 way active avoidance conditioning



Revista Brasileira de Biologia 41(3): 599-606



The effect of the association of diphenylhydantoin and amphetamine or nicotine was studied in rats submitted to 2 way active avoidance conditioning. Amphetamine administered pre-trial antagonized the effect of diphenylhydantoin. Nicotine did not produce this effect. Diphenylhydantoin alone or associated with amphetamine or nicotine, when administered post-trial, did not affect retention. Diphenylhydantoin impaired the active avoidance conditioning in previously trained rats. This effect was antagonized by amphetamine, but not by nicotine.

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Accession: 005329575

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