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Effects of the beta agonist cimaterol on blood metabolite and hormone concentrations growth and carcass composition in finishing friesian steers



Effects of the beta agonist cimaterol on blood metabolite and hormone concentrations growth and carcass composition in finishing friesian steers



Journal of Animal Physiology & Animal Nutrition 60(3): 128-136



The effect of the beta-adrenergic agonist, cimaterol on the performance and carcass composition of finishing Friesian steers was examined. Four groups of 15 steers each were offered grass silage ad libitum and 4 kg of a pelleted concentrate supplement head-1 day-1 which contained either 0, 33, 49.5, or 66 mg cimaterol, for a 91 day test period. The control supplement was then offered to all animals for 7 days prior to slaughter. Inclusion of cimaterol in the diet enhanced growth rate and feed efficiency by up to 30% but did not influence feed intake. Treatment with cimaterol increased the killing-out percentage by more than 4 units and carcass weight by up to 30 kg. Subcutaneous fat and conformation grades also improved significantly as a result of treatment with cimaterol. Cimaterol reduced the weight of the kidney and pelvic fat depot and the proportion of separable fat in the carcass by up to 40%. The increase in lean meat yield and longissimus dorsi muscle area as a result of treatment averaged 16 and 42% respectively. Analysis of blood samples taken on day 85 of treatment revealed no evidence for any effect of cimaterol on growth hormone, somatomidin C, triglycerides or glucose concentration. Cimaterol reduced concentrations of urea nitrogen and insulin and significantly increased concentrations of creatinine, free fatty acid, alanine aminotransferase and aspartate aminotransferase in blood. These data demonstrate the potential of cimaterol as an agent to improve cattle performance and muscle accretion with a concommitant reduction in carcass fat.

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