EurekaMag
+ Translate
+ Most Popular
Gaucher's disease;thirty-two years experience at Siriraj Hospital
A study of Macrobathra Meyrick from China (Lepidoptera, Cosmopterigidae)
First occurrence in ores of tetragonal chalcocite
Effects of trace element nutrition on sleep patterns in adult women
N.Z. range management guidelines. 2. Design of grazing management systems for tussock country
A case of lipoma of the esophagus
A revision of world Acanthosomatidae (Heteroptera: Pentatomidae): keys to and descriptions of subfamilies, tribes and genera, with designation of types
Life history of the coronate scyphozoan Linuche unguiculata (Swartz, 1788)
Perceptual restoration of obliterated sounds
Mutagenicity studies on two chromium(III) coordination compounds
The formation of the skeleton. I. Growth of a long bone. 1st appearance of a center of calcification
Leucopenia and abnormal liver function in travellers on malaria chemoprophylaxis
The joint commission: four key root causes loom large in sentinel event data
Treatment of vitiligo with topical 15% lactic acid solution in combination with ultra violet-A
Behaviour of dairy cows within three hours after feed supply: I. Influence of housing type and time elapsing after feed supply
Observations of the propagation velocity and formation mechanism of burst fractures caused by gunshot
Management and control of patients with type 2 diabetes mellitus in Lebanon: results from the International Diabetes Management Practices Study (IDMPS)
The diet composition and nutritional knowledge of patients with anorexia nervosa
Physoporella croatica Herak, 1958 of the Slovak karst Anisian (Slovakia, the West Carpathians Mts.)
Bright lights, big noise. How effective are vehicle warning systems?
Ein Plesiosaurier-Rest mit Magensteinen aus mittlerem Lias von Quedlinburg
Incidence of Chlamydia trachomatis in patients with sterility
Monster soup: the microscope and Victorian fantasy
Preliminary tests with residual sprays against poultry lice
Duration of the life of plants in phylogeny

Effects of treatment with thiamin antagonists, oxythiamin and pyrithiamin and of thiamin excess of the levels and distribution of thiamin in rat tissues


Effects of treatment with thiamin antagonists, oxythiamin and pyrithiamin and of thiamin excess of the levels and distribution of thiamin in rat tissues



Journal of Nutritional Science and Vitaminology 28(3): 217-224



ISSN/ISBN: 0301-4800

PMID: 7131099

Levels of thiamin and its derivatives in brain, heart and liver were determined in control, thiamin-deficient, pyrithiamin-treated and oxythiamin-treated rats at various times after the start of treatment. With 10 .mu.g of thiamin/100 g per day s.c. rats rapidly lost thiamin from the tissues until growth maintenance levels were reached. Oxythiamin had a minimal further effect on tissue thiamin while pyrithiamin caused further marked reduction. With higher levels of thiamin intake, tissue thiamin levels increased with intakes of up to 150-200 .mu.g/100 g per day after which they did not show any further significant increase. Levels of pyrithiamin above 50 .mu.g/100 g per day for 20 days had only minimal further effect on tissue thiamin levels over that with 50 .mu.g.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 005331660

Download citation: RISBibTeXText

Related references

Blood and serum thiamin and thiamin phosphate esters concentrations in patients with alcohol dependence syndrome before and after thiamin treatment. Alcoholism Clinical and Experimental Research 16(2): 320-325, 1992

Blood and serum thiamin and thiamin phosphate esters concentrations in patients with alcohol dependence syndrom before and after thiamin treatment. Alcoholism, Clinical and Experimental Research 16(2): 320-325, 1992

Blood thiamin and thiamin phosphate esters in patients with alcohol dependence syndrome before and 24 hrs after thiamin injection. Clinical Nutrition (Edinburgh) 10(SPEC Suppl 2): 23, 1991

Chemical behavior of isolated thiamin ylide in neutral aqueous solution a new mechanism of interconversion of thiamin and thiamin thiolate. Heterocycles 26(1): 13-18, 1987

Nervous tissue thiamin metabolism in vivo 1. transport of thiamin and thiamin mono phosphate from plasma to different brain regions of the rat. Brain Research 293(2): 319-328, 1984

Dietary thiamin supply during lactation influences thiamin status in lactating rats and their offspring and the thiamin level in milk. Zeitschrift für Ernahrungswissenschaft 36(2): 169-175, 1997

Behaviour of thiamin and its phosphate esters in thiamin deficiency in isolated rat liver perfused with thiamin. Arch. Sci. biol 53: 58-72, 1969

Intestinal thiamin transport in rats. Thiamin and thiamin phosphoester content in the tissue and serosal fluid of everted jejunal sacs. Pflugers Archiv: European Journal of Physiology 393(1): 37-41, 1982

Synthesis and crystal structure of an analog of 2 alpha lactyl thiamin racemic methyl 2 hydroxy 2 2 thiamin ethyl phosphonate chloride tri hydrate a conformation for a least motion maximum overlap mechanism for thiamin catalysis. Journal of the American Chemical Society 104(11): 3089-3095, 1982

Nitrogen and thiamin supply and fungal fructification a 2 factor analysis 2. the influence of the thiamin and nitrogen content of the substrate on the thiamin concentration in the fruitbodies of 2 basidiomycetes. Beitraege zur Biologie der Pflanzen 60(2): 223-242, 1985

Effects of Thiamin Deficiency and Thiamin Antagonists on Serum and Liver Cholesterol Levels and on Cholesterol Biosynthesis in Rats. The Journal of Nutrition 104(12): 1690-1695, 1974

Effects of thiamin deficiency and thiamin antagonists on serum and liver cholesterol levels and on cholesterol biosynthesis in rats. Journal of Nutrition 104(12): 1690-1695, 1974

The activity of thiamin dependent enzymes in candida lipolytica growing on glucose under the conditions of thiamin excess and deficiency. Mikrobiologiya 55(4): 559-563, 1986

The effect of a thiamin analogue on growth and on the thiamin content of rat tissues. American Journal of Veterinary Research 10(34): 77-84, 1949

Transketolase, pyruvate and oxoglutarate dehydrogenase activities and [14C]thiamin turnover in tissues of mice fed thiamin-deficient diet. Journal of Nutrition 113(7): 1285-1291, 1983