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Electrophoretic comparison of the genomes of north american bluetongue viruses 1 australian bluetongue virus and 3 other related orbiviruses

Electrophoretic comparison of the genomes of north american bluetongue viruses 1 australian bluetongue virus and 3 other related orbiviruses

Veterinary Microbiology 7(4): 285-294

The genomes of USA bluetongue viruses, an Australian bluetongue virus and 3 other related orbiviruses [2 epizootic hemorrhagic disease of deer virus serotypes and Ibaraki virus] were analyzed by polyacrylamide gel electrophoresis. The genomes were comprised of 10 segments of double-stranded (ds)RNA. Estimates of the MW of the dsRNA segments revealed that the USA bluetongue serotypes were remarkably similar. Although the dsRNA profiles of the viruses exhibited common segments, each virus had a distinct dsRNA profile. The usefulness of the genome analysis as a diagnostic tool for identification and for epidemiologic studies is discussed.

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Accession: 005348464

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