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Electrophoretic variants of blood proteins in japanese 1. phosphoglucomutase 2


, : Electrophoretic variants of blood proteins in japanese 1. phosphoglucomutase 2. Japanese Journal of Human Genetics 29(2): 89-104

A total of 17,126 individuals, of whom 11,833 are unrelated, living in Hiroshima nad Nagasaki were examined for erythrocyte phosphoglucomutase-2 (PGM2) by starch gel electrophoresis using TEMM buffer, pH 7.4. Four kinds of hereditary rare variants were encountered, 3 detected in single families and 1 remaining in 9 unrelated families. A fresh mutant whose main band migrated slightly cathodal to the d-band was detected in a male child in Nagasaki, whose parents were proximally exposed to the atomic bomb in that city. The results confirm previous data that PGM2 variation is quite low among the Japanese.

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