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Electrophoretic variation for x chromosome linked hypo xanthine phospho ribosyl transferase ec 2.4.2.8 in wild derived mice


, : Electrophoretic variation for x chromosome linked hypo xanthine phospho ribosyl transferase ec 2.4.2.8 in wild derived mice. Genetics 103(4): 785-796

An electrophoretic variation for hypoxanthine phosphoribosyltransferase, HPRT, was identified in samples of Mus spretus, a field mouse from southern Europe and in M. musculus castaneus, a house mouse from southeast Asia. These mice will interbreed with laboratory mice to produce viable, fertile F1 progeny. The variation for HPRT segregates as an X chromosome gene in F1 and backcross progeny. Linkage analysis involving the markers Pgk-1 and Ags indicated a gene order of centromere-Hprt-Pgk-1-ags in crosses involving both stocks of wild mice.

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