+ Site Statistics
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Electrophoretically controlled dermal or transdermal application systems with electronic indicators

, : Electrophoretically controlled dermal or transdermal application systems with electronic indicators. International Journal of Pharmaceutics (Kidlington) 36(1): 37-40

The present investigation describes a system for the local application of basic drugs to the skin, using the antihistamine diphenhydramine hydrochloride as an example in which the release of the drug from a gel-type carrier is controlled by a weak electric field. In vitro studies of the release of drug showed that for example, through the application of 9 V, the amount of diphenhydramine hydrochloride released from a gel carrier in 5 min can be increased by a factor of 2.5. A newly developed, pencil-shaped application system contains an integrated voltage supply and an electronic indicator to show when the system is in operation. Investigations in 6 subjects of the current flow and electrical resistance of the human body show that the current through the body caused by the drug pencil is about 86 .mu.A.

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 005349205

DOI: 10.1016/0378-5173(87)90233-X

Download PDF Full Text: Electrophoretically controlled dermal or transdermal application systems with electronic indicators

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

Pérez, J.; Riera, Lía., 2008: Stable metal-organic complexes as anion hosts. A growing number of metal-organic complexes are being employed as anion hosts. This tutorial review focuses on stable, mononuclear transition metal complexes with a well defined geometry that use a combination of electrostatic attraction and hydro...

Proctor, L.M.; Woodruff, T.M.; Sharma, P.; Shiels, I.A.; Taylor, S.M., 2006: Transdermal pharmacology of small molecule cyclic C5a antagonists. Overproduction or underregulation of the proinflammatory complement component C5a has been implicated in numerous immune and inflammatory conditions. Therefore, targeting the C5a receptor (C5aR) has become an innovative strategy for antiinflammato...

Powers L.R.; Draeger S., 1992: Teaching procedures to residents description of a method. Clinical Research 40(2): 603A

Katili J. A., 1965: Advances of geology and related activities in Indonesia 1961-1965. Results of geologic research carried out in 1961-65 in the fields of geomorphology, structural geology, volcanology and petrology, and paleontology and stratigraphy are summarized. Geologic expeditions have been conducted and exploration for new p...

Falkert, A.; Yildiz, A.; Seelbach-Goebel, B., 2008: Partial mole with fetal triploidy as a cause for imminent HELLP-syndrome at 16 weeks of gestation. A woman at 16 weeks of gestation was admitted to our perinatal center with unspecific abdominal pain. The results from blood samples 12 h after admission revealed a fulminant HELLP-syndrome. After starting i.v. corticosteroid therapy, the woman re...

Batten, L.; Dutton, J., 2012: Young tertiary students and help-seeking for health advice. Help-seeking is an active process used by people of all ages to obtain assistance to solve problems. This research sought to investigate a component of help-seeking related to health concerns. A health related help-seeking model, was adapted to fr...

Newsom-Davis, J., 1994: High hopes ... for neurology. A view from the top. Journal of the Royal College of Physicians of London 28(2): 105-105

Claus, C., 1886: Ueber Lernaeascus nematoxys, eine seither unbekannt gebliebene Lernaea. Morphological description; parasitic under scales of Solea monochir.

Keddam-Malplanche, M., 1980: Comparative palynological study of climbing species in the genera Sherbournia and Porterandia (Rubiaceae, Gardenieae). Adansonia 9(4): 429-434

Deichsel Guntram; Ansermet Michel, 2012: Podarcis muralis common wall lizard saurophagy. Herpetological Review 43(3): 489