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Electrophysiological and catecholamine negative feedback mechanisms in hypothalamic regulation with male sex glands


, : Electrophysiological and catecholamine negative feedback mechanisms in hypothalamic regulation with male sex glands. Byulleten' Eksperimental'noi Biologii i Meditsiny 97(6): 722-725

The immediate response on the part of the sympathoadrenal system (SAS) in mature male rats to testosterone propionate involves an increase in the content of dopamine and lowering of adrenaline [epinephrine] and noradrenaline [norepinephrine] content in the hypothalamus, brain cortex, adrenals and peripheral organs, paralleled by an increase in the amplitude of evoked potentials and reduction in the frequency of induced impulse activity of arcuate neurons of the hypothalamus. This attests to the specificity of the associated responses of the SAS and the hypothalamus-pituitary-gonadal system (HPGS) to hyperandrogenization and to the dopaminergic nature of the negative feed-back mechanism in the HPGS.

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