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Electrophysiological and ultrastructural study of the active zone topography in the frog's motor nerve terminal

Doklady Akademii Nauk SSSR 290(5): 1277-1280
Electrophysiological and ultrastructural study of the active zone topography in the frog's motor nerve terminal
A complex physiological and electron-microscopic study of the topography, function and ultrastructure of the active zone was made in various portions of the motor ending of the frog. Electrophysiological experiments were carried out in neuromuscular specimens from the tailor's muscle of Rana ridibunda. An analysis of the nerve ending ultrastructure demonstrated considerable differences in the structure of proximal and distal portions. The results showed that various terminal portions are functionally and structurally heterogenous. Morphological differences of active zones related to the characteristics of mediator secretion made it possible to presume that the change in the active zone is one of possible regulatory mechanisms of the effectiveness of synaptic transmission.

Accession: 005349463

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