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Electrophysiological characterization of histamine receptor subtypes in mammalian heart preparations

, : Electrophysiological characterization of histamine receptor subtypes in mammalian heart preparations. Naunyn Schmiedeberg's Archives of Pharmacology 334(3): 294-302

Histamine-induced electrophysiological effects have been investigated in guinea-pig left atria, papillary muscles and rabbit AV-nodal preparations by means of intracellular recording of action potentials, slow responses in the presence of 27 mmol/l (K+)o and voltage clamp experiments.

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Accession: 005349493

PMID: 2433604

DOI: 10.1007/bf00508785

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Montero, R.; Yubero, D.; Villarroya, J.; Henares, D.; Jou, C.; Rodríguez, M.Angeles.; Ramos, F.; Nascimento, Aés.; Ortez, C.Ignacio.; Campistol, J.; Perez-Dueñas, B.; O'Callaghan, M.; Pineda, M.; Garcia-Cazorla, A.; Oferil, J.Colomer.; Montoya, J.; Ruiz-Pesini, E.; Emperador, S.; Meznaric, M.; Campderros, L.; Kalko, S.G.; Villarroya, F.; Artuch, R.; Jimenez-Mallebrera, C., 2016: GDF-15 Is Elevated in Children with Mitochondrial Diseases and Is Induced by Mitochondrial Dysfunction. We previously described increased levels of growth and differentiation factor 15 (GDF-15) in skeletal muscle and serum of patients with mitochondrial diseases. Here we evaluated GDF-15 as a biomarker for mitochondrial diseases affecting children a...

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