+ Site Statistics
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Electrophysiological evidence that nipecotic acid can be used in vivo as a false transmitter

, : Electrophysiological evidence that nipecotic acid can be used in vivo as a false transmitter. Brain Research 335(2): 377-380

Dentate gyrus of the rat hippocampal formation was perfused with the potent inhibitor of GABA uptake, nipecotic acid, by means of an implanted dialytrode. Evoked population spikes in dentate gyrus were decreased in amplitude and often abolished during perfusion. Multiple (2-4) population spikes developed shortly after nipecotic acid withdrawal. This excitability increase, which presented a pattern of repetitive discharge resembling that following blocking of GABAergic transmission was interpreted as electrophysiological evidence that nipecotic acid can act as a false transmitter in vivo, as postulated from uptake and release in vitro studies.

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 005349653

PMID: 2860948

DOI: 10.1016/0006-8993(85)90498-6

PDF Full Text: Electrophysiological evidence that nipecotic acid can be used in vivo as a false transmitter

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

Kasai, M.; Meguro, K.; Nakamura, K., 2016: Reliability and validity of the Japanese version of the Apathy Evaluation Scale. Clinicians need an objective scale to measure apathy in patients with dementia. However, different cutoff scores for the Apathy Evaluation Scale Informant version (AES-I), an international apathy scale, have been used in previous studies. The purp...

Heitkemper, M.; Landis, C.A.; Fugate Woods, N., 2010: Women's health across the life span: contributions from nursing science. Biological Research for Nursing 12(1): 5-6

Srivastava, S.C.; Jha, A.K.; Singh, J.S., 1989: Changes with time in soil biomass C, N and P of mine spoils in a dry tropical environment. Soil biomass C, N and P were determined for a native forest site, an unmined deforested site and an age-series of adjacent coal mine spoils (5, 10, 12, 16 and 20 yr). Biomass C ranged from 209 to 867 mu g g-1 soil, biomass N from 20 to 75 mu g g...

REED, H., 1960: Chymotrypsin in cataract surgery. Canadian Medical Association Journal 82: 767-770

Teshima, R.; Otsuka, T.; Takasu, N.; Yamagata, N.; Yamamoto, K., 1995: Structure of the most superficial layer of articular cartilage. We studied the most superficial layer of macroscopically normal articular cartilage obtained from human femoral heads, using polarising microscopy and SEM. The most superficial layer, 4 to 8 microns thick, was acellular consisting of collagen fibr...

Reichenow, A., 1918: Nachtrag uber einige Vogel von Kurland. Journal fuer Ornithologie Leipzig, 66 407-408

Bar-Tana, J.; Rose, G.; Shapiro, B., 1971: The purification and properties of microsomal palmitoyl-coenzyme A synthetase. The isolation and purification of palmitoyl-CoA synthetase from rat liver microsomes is described. Several methods suitable for enzyme assay are described. The general properties and kinetic parameters of the purified enzyme were determined and ar...

Chen, L.; Redwood, S.; Chester, M.R.; Huang, J.; Leatham, E., 1994: Comparative progression of ischemia-related stenosis and mild stenosis in stable angina versus unstable angina. Circulation 90(4 PART 2): I450

Gervy, R., 1983: Uses and methods of application of phosphate fertilizers. Phosphorus fertilizer rates are determined by P content in the soil and crop requirements. Proposed rates are confirmed by field trials taking into account economic factors. The amount of money used for fertilization depends closely on the agricul...

Wenzel K.W.; Weise W.; Kotulla H.P.; Schleusener H.; Adlkofer F., 1976: Different association of histo compatibility antigens in patients with graves disease or autonomous adenoma and its correlation to human thyroid stimulating globulins. Acta Endocrinologica Supplementum 204: NO