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Electrophysiological responses of hamster suprachiasmatic neurons to neuropeptide y in the hypothalamic slice preparation

, : Electrophysiological responses of hamster suprachiasmatic neurons to neuropeptide y in the hypothalamic slice preparation. Neuroscience Letters 80(2): 173-179

The rate and pattern of neuronal discharge in the hamster suprachiasmatic nucleus (SCN) was studied using an in vitro hypothalamic slice preparation. The firing rate of hamster SCN neurones (n = 183 cells) exhibited a circadian variation similar to that reported in the rat. SCN neurons tested for responses to pressure ejection of neuropeptide Y (NPY) (n=49) were either tonically excited (65%) or unresponsive (35%). There was a tendency for more NPY-responsive cells to be recorded during the light phase of the circadian light-dark cycle.

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