+ Site Statistics
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Electrophysiological study on animal model of depression single unit activity of locus coeruleus neurons in rats exposed to long term severe stress

, : Electrophysiological study on animal model of depression single unit activity of locus coeruleus neurons in rats exposed to long term severe stress. Mie Medical Journal 37(1): 1-16

The spontaneous and evoked activity of locus coeruleus neurons was studied by extracellular recording in the following three groups of rats exposed to forced running stress: 3-day stress rats, which were stressed for three days, depression-model rats, which remained inactive after long-term forced running stress, and recovery rats, which gradually recovered from the inactive state after the long-term stress. The spontaneous firing rates tended to decrease in 3-day stress rats. In depression-model rats, the rate significantly decreased in comparison with that in control and recovery rats. The rate in recovery rats was the same as in control rats. The number of evoked spikes in response to foot-shock also significantly decreased in depression-model rats. The inhibitory effect of imipramine on the spontaneous firing rate was more marked in depression-model rats. These findings suggest that unit activity of locus coeruleus neurons is decreased in depression-model rats.

(PDF 0-2 workdays service)

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 005349864

PDF Full Text: Submit

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

Appel, Katrin; Schneider, Eberhard; Wagner, Peter; Hoog, Jan Olov; Karlsson, Christina; Montenarh, Mathias, 1994: A new 42 KDa protein binding to the growth suppressor protein p53. Expression of the growth suppressor gene p53 in Schizosaccharomyces pombe causes growth arrest which can be suppressed by overexpression of a yeast gene termed tms1. The tms1 gene encodes a 37 KDa protein which binds to p53 in vitro and in vivo wh...

Highton T.C.; Myers D.B.; Rayns D.G., 1972: Filaments inter connecting collagen fibrils. Australian & New Zealand Journal of Medicine 2(3): 338

Kovach J., 1979: Road log for day one (May 12, 1979); Pittsburgh, Pennsylvania to New Concord, Ohio; Upper Carboniferous stratigraphy and depositional environments of eastern Ohio. Pages 30-52 1979

An DongShan; Im WanTaek; Yang HeeChan; Lee SungTaik, 2006: Shinella granuli gen. nov., sp. nov., and proposal of the reclassification of Zoogloea ramigera ATCC 19623 as Shinella zoogloeoides sp. nov. The taxonomic position of a novel bacterial strain, Ch06T, isolated from an upflow anaerobic sludge blanket reactor was determined. Strain Ch06T was Gram-negative, aerobic, motile and oxidase- and catalase-positive. A comparative 16S rRNA gene seq...

Fukui, T.; Kakiuchi, N.; Ikehara, M., 1978: Poly nucleotides part 44 synthesis and properties of poly 2 aza adenylic acid and poly 2 aza inosinic acid. Chemically synthesized 2-azaadenosine 5'-diphosphate (n2ADP) and 2-azainosine 5'-diphosphate (n2IDP) were polymerized to yield poly(2-azaadenylic acid), poly(n2A) and poly(2-azainosinic acid), poly(n2I), using Escherichia coli polynucleo...

Gardner, Richard, L.; Brook, Frances, A., 1997: Reflections on the biology of embryonic stem (ES) cells. Remarkably little is known about mammalian embryonic stem (ES) cells despite their very widespread use in studies on gene disruption and transgenesis. As yet, it is only in the mouse that lines of ES cells which retain the ability to form gametes...

Trivedi, Bijal, 1999: Biology comes out of its shell. Nature Biotechnology 17(4): 0

Bex, Marie; Abs, Roger; Maiter, Dominique; Beckers, Albert; Lamberigts, Gerard; Bouillon, Roger, 2002: The effects of growth hormone replacement therapy on bone metabolism in adult-onset growth hormone deficiency: A 2-year open randomized controlled multicenter trial. Adult hypopituitary patients with growth hormone deficiency (GHD) show a significant decrease in bone mass and an increased fracture rate. Replacement therapy with GH increases bone turnover. Most of the long-term data on bone mineral content (BMC...

Donati, Guy; Pournaras, Constantin J.; Pizzolato, Gian Paolo; Tsacopoulos, Marco, 1997: Decreased nitric oxide production accounts for secondary arteriolar constriction after retinal branch vein occlusion. Purpose. After retinal branch vein occlusion (BVO), the arteriole crossing the occluded territories is often constricted. This constriction persists up to several weeks and is correlated with the development of extended territories of nonperfused...

Papunen H., 1996: Ni-Cu deposits in intrusive mafic-ultramafic rocks; a review. Publication Series - Australasian Institute of Mining and Metallurgy Pages 123-129