EurekaMag.com logo
+ Site Statistics
References:
52,725,316
Abstracts:
28,411,598
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Electrophysiology and morphology of growth hormone producing cells of lymnaea stagnalis


Proceedings of the Koninklijke Nederlandse Akademie van Wetenschappen Series C Biological & Medical Sciences 88(1): 129-141
Electrophysiology and morphology of growth hormone producing cells of lymnaea stagnalis
The neuroendocrine growth hormone producing cells in the cerebral ganglia of L. stagnalis are morphologically organized in 2 separate, bilaterally located, sub-systems each consisting of 2 clusters of cell-bodies. All axons of each sub-system run together in 1 bundle towards an ipsilateral neurohemal area. In this respect the growth hormone system differs from the neuroendocrine ovulation hormone system of this snail; all ovulation hormone producing cells end in one common neurohemal area and all are electrotonically connected. In other aspects there are similarities. Both cell types show great changes in excitability. A striking difference in excitability was found between growth hormone producing cells in directly isolated cerebral ganglia and those in implanted cerebral ganglia; this observation caused a breakthrough in the investigation of these cells. The second part of the present work deals with the characteristics of ionic channels of the growth hormone producing cells. A TTX[tritiated tetrodotoxin]-sensitive Na+-channel is present, and in addition Ca2+-ions also carry inward current. Agents like Ba2+-ions and 4-aminopyridine, which interfere with K+-conducting channels are able to bring about repetitive electrical activity. It may be that factors which regulate the secretion of the growth hormone do this by means of alterations of the K+-permeability. The characteristics of the ovulation hormone and the growth promoting systems are compared.


Accession: 005349878



Related references

Morphology and electrophysiology of the ovulation hormone producing neuro-endocrine cells of the freshwater snail Lymnaea stagnalis (L.). Journal of Experimental Biology 84: 259-271, 1980

Morphology of neurosecretory cells in basommatophoran snails homologous with egg-laying and growth hormone-producing cells of Lymnaea stagnalis. General and Comparative Endocrinology 67(1): 7-23, 1987

Morphology and electro physiology of the ovulation hormone producing neuro endocrine cells of the fresh water snail lymnaea stagnalis. Journal of Experimental Biology 84: 259-271, 1980

Further pharmacological characterization of a D-2-like dopamine receptor on growth hormone producing cells in Lymnaea stagnalis. European Journal of Pharmacology 139(2): 155-161, 1987

Growth hormone producing cells in lymnaea stagnalis as a model system for mammalian dopamine receptors. Trends in Pharmacological Sciences 7(none): 7-9, 1986

Excitability in growth hormone producing cells of the mollusk lymnaea stagnalis is controlled by dopaminergic receptors. Neuroscience Letters (SUPPL 18): S312, 1984

Morphological and elcetrophysiological features of the growth hormone producing light green cells of Lymnaea stagnalis. Unknown, 1983

Change in excitability in growth hormone producing cells of Lymnaea stagnalis induced by dopamine receptor stimulation. Unknown, 1987

Localization of dopamine and its relation to the growth hormone producing cells in the central nervous system of the snail Lymnaea stagnalis. Experimental Brain Research 85(1): 1-9, 1991

Opposing roles for D-1 and D-2 dopamine receptors in regulating the excitability of growth hormone-producing cells in the snail Lymnaea stagnalis. European Journal of Pharmacology, 1062: 431-435, 1985