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Electrophysiology of ascending possibly cholinergic neurons in the rat laterodorsal tegmental nucleus comparison with monoamine neurons


, : Electrophysiology of ascending possibly cholinergic neurons in the rat laterodorsal tegmental nucleus comparison with monoamine neurons. Neuroscience Letters 77(3): 277-282

In urethane-anesthetized rats single neuronal activity was recorded in the laterodorsal tegmental nucleus (LDT), which has a dense complement of cholinergic neurons, and in the dorsal raphe and locus coeruleus for comparison. Most LDT neurons responded antidromically to stimulation of either one or more of several rostral loci, and gave rise to broad spikes. They showed various properties very similar to those of monoaminergic neurons. Others generated brief spikes. The former may be cholinergic. The most frequent response of broad-spike LDT neurons to noxious stimulation was phasic excitation, which tended to become weak or disappear upon repetition.

Accession: 005349885

PMID: 3614760

DOI: 10.1016/0304-3940(87)90512-X

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Related references

Grant S.J.; Highfield D.A.; Piser T., 1988: Electrophysiology of putative ch6 cholinergic neurons in the laterodorsal tegmental nucleus. Society for Neuroscience Abstracts 14(2): 905

Kayama, Y.; Koyama, Y., 1993: Sensory responses of possibly cholinergic neurons in the rat laterodorsal tegmental nucleus. Society for Neuroscience Abstracts 19(1-3): 1818

Kayama Y.; Ohta M., 1990: Firing of possibly cholinergic neurons in the laterodorsal tegmental nucleus of the rat during wakefulness and sleep. Society for Neuroscience Abstracts 16(2): 1255

Kayama Y.; Ohta M.; Jodo E., 1992: Firing of possibly cholinergic neurons in the rat laterodorsal tegmental nucleus during sleep and wakefulness. To clarify functional roles of mesopontine cholinergic neurons as a component of an activating system, single neuronal activity in the laterodorsal tegmental nucleus (LDT) of undrugged rats, whose head was fixed painlessly, was recorded along with...

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