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Electroretinogram and visual evoked cortical potential in chronic progressive external ophthalmoplegia


Klinische Monatsblaetter fuer Augenheilkunde 185(2): 113-118
Electroretinogram and visual evoked cortical potential in chronic progressive external ophthalmoplegia
Patients (11) suffering from chronic progressive external ophthalmoplegia (CPEO) were examined by means of electroretinography (ERG) and the visually evoked cortical potential (VECP) with flash and checkerboard-reversal stimuli. One patient exhibited a Kearns-Sayre syndrome, and in 2 patients fundoscopy revealed pigmentary retinopathy; the fundi of the other 8 patients were normal. In 3 of the patients with pigmentary retinopathy the ERG was slightly disturbed or normal, the P100 latency in the VECP was normal. In 3 out of 8 patients without retinal pigmentary changes, the ERG indicated retinopathy. In 2 cases this was the only finding offering an explanation for the reduced visual acuity. One patient exhibited a considerably prolonged P100 latency in the pattern-reversal VECP of 1 eye, which may be indicative of lesions of the visual pathway associated with CPEO.


Accession: 005349938



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