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Emergency surgery and refractory immune thrombocytopenic purpura. A case report



Emergency surgery and refractory immune thrombocytopenic purpura. A case report



South African Medical Journal 69(5): 321-322



A 35-year-old woman with post-splenectomy refractory immune thrombocytopenia presented with an acute abdominal emergency requiring laparotomy. Her platelet count was raised from 10 to 96 .times. 109/l using a combination of high-dose methylprednisolone, plasma exchange against fresh-frozen plasma, infusion of gammaglobulin and a single mega-unit of platelets. The surgical procedure was uneventful, and with no further therapy the platelet count rose to a peak of 244 .times. 109/l, but over the following 7 days fell back slowly to 10 .times. 109/l, at which time the patient was discharged well.

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Accession: 005354273

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PMID: 2421418



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