EurekaMag.com logo
+ Site Statistics
References:
53,869,633
Abstracts:
29,686,251
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Endorphin activity in childhood psychosis. Spinal fluid levels in 24 cases



Endorphin activity in childhood psychosis. Spinal fluid levels in 24 cases



Archives of General Psychiatry 42(8): 780-783



Twenty 2- to 13-year-old infantile autistic children (16 boys and four girls) and four 4- to 13-year-old children (two boys and two girls) with other kinds of childhood psychoses were compared with eight 6-month-old to 6-year-old normal children with regard to cerebrospinal fluid contents of endorphin fractions I and II. The psychosis groups showed higher mean cerebrospinal fluid endorphin fraction II levels, and 11 (55%) of the 20 autistic patients showed values higher than the highest in the group of normal children. There was a trend toward a correlation between high fraction II levels and self-destructiveness and decreased pain sensibility in the psychotic children. The results are regarded as preliminary but as warranting further research in this potentially fruitful field.

(PDF emailed within 1 workday: $29.90)

Accession: 005359013

Download citation: RISBibTeXText

PMID: 4015322



Related references

Leukemic blasts are present at low levels in spinal fluid in one-third of childhood acute lymphoblastic leukemia cases. Pediatric Blood & Cancer 63(11): 1935-1942, 2016

Childhood psychosis and monoamine metabolites in spinal fluid. Journal of Autism and Developmental Disorders 13(4): 383-396, 1983

Plasma and cerebro spinal fluid endorphin levels during pregnancy. Anesthesiology (hagerstown)ppl. 3): A380, 1982

Endorphin like activity in human cerebro spinal fluid. Neuroscience Letters SUPPL(1): S243, 1978

Progressive impairment of cerebro spinal fluid beta endorphin levels in migraine sufferers. Pain 18(2): 127-134, 1984

Cyclic amp levels in the cerebro spinal fluid of manic depressive psychosis. Neurochemical Research 3(5): 655, 1978

Increased cerebro spinal fluid levels of endorphines in chronic psychosis. Neuroscience Letters 3(3): 157-162, 1976

Increased beta endorphin but not methionine enkephalin levels in human cerebro spinal fluid after acupuncture for recurrent pain. Lancet 2(8201): 946-948, 1980

Evidence of disturbed cerebro spinal fluid circulation and brain atrophy in cases of schizophrenic psychosis. British Journal of Psychiatry 144(JUNE): 654-661, 1984

Spinal fluid lysozyme levels in childhood meningitis. Monatsschrift Kinderheilkunde 128(11): 717-719, 1980

Spinal manipulation and beta-endorphin: a controlled study of the effect of a spinal manipulation on plasma beta-endorphin levels in normal males. Journal of Manipulative and Physiological Therapeutics 9(2): 115-123, 1986

Spinal manipulation and beta-endorphin: a controlled study of the effect of a spinal manipulation of plasma beta-endorphin levels in normal males. Journal of Manipulative and Physiological Therapeutics 10(1): 31-32, 1987

Depression and cerebro spinal fluid endorphin fraction 1. seasonal variation and higher levels in uni polar than bi polar patients. Psychiatry Research 10(4): 303-311, 1983

Beta endorphin beta lipotropin and acth levels in cerebro spinal fluid and brain damage in chronic alcoholics. European Neurology 22(4): 265-271, 1983

Endogenous opioid activity and beta endorphin immuno reactivity in cerebro spinal fluid of psychiatric patients and normal volunteers. American Journal of Psychiatry 138(11): 1457-1462, 1981