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Endorphins and the lower urinary tract



Endorphins and the lower urinary tract



Urologia Internationalis 39(3): 175-177



In order to investigate the influence of the endorphins on lower urinary tract function the endogenous opiates were antagonized with naloxone. Urodynamic examinations were performed in 17 incontinent women both before and after the administration of i.v. 0.4 mg naloxone. Bladder volume and pressure were not influenced by naloxone; the maximum urethral pressure showed a slight and urethral closure pressure a significant rise after naloxone treatment. A role of endorphins in lower urinary tract function was not supported.

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Accession: 005359044

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