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Endoscopic diagnosis of the extent of mucosal infiltration of depressed early gastric cancer by pharmacoendoscopy with special reference to endoscopic color and vascular beds in cancerous mucosa by image analysis



Endoscopic diagnosis of the extent of mucosal infiltration of depressed early gastric cancer by pharmacoendoscopy with special reference to endoscopic color and vascular beds in cancerous mucosa by image analysis



Gastroenterological Endoscopy 28(3): 493-507



A clinical endoscopic observation was carried out to determine the extent of mucosal infiltration of flat or depressed early gastric cancers, by spraying epinephrine and prostaglandin E1 (PEP). In effective cases of cancer lesions, their enhanced areas appeared red and were surrounded by discolored normal mucosa. To clarify the mechanism of the PEP, the ratio of vascular beds in cancerous mucosa to normal mucosa of the oral side [C/N ratio-U (upper layer), C/N ratio-T (total layer)] was calculated using an image analysis system. A study was also made on the relation of the C/N ratio-U to endoscopic color of gastric cancer lesions and histological types. The results obtained were as follows: 1. Endoscopic color or early gastric cancer was found to be determined by the C/N ratio-U rather than the C/N ratio-T (0.05

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Accession: 005359194

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