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Endoscopic differential diagnosis of giant folds

Endoscopic differential diagnosis of giant folds

Stomach & Intestine 15(5): 509-518

Diseases which cause giant folds in the stomach, [Menetrier's disease and other benign types as well as malignant ones such as Borrmann's type 4 gastric cancer and malignant lymphoma] were studied. A survey of cases having giant folds and the critical points necessary for endoscopic differentiation of the disease were discussed. Of 19 cases classified as benign giant folds, 2 cases of Menetrier's disease were described. The distensibility of the gastric wall was excellent and mucus secretion was enhanced. No erosion or ulceration was seen. Of the 177 cases of Borrmann's type 4 gastric cancer, 114 cases (64%) had giant folds, most of which had some degree of erosion or ulceration combined. Differentiation of such cases from benign giant folds is a problem, but by observing various endoscopic characteristics, it can be done without much confusion. Of the 20 cases of malignant lymphoma of the stomach, 5 had giant folds (5%), all combined with polypoid lesion or ulceration.

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Accession: 005359200

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