+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Endoscopic findings in sleep apnea associated with acromegaly

Endoscopic findings in sleep apnea associated with acromegaly

Journal of Clinical Endocrinology and Metabolism 55(1): 18-22

Two acromegalic patients presented with the additional complaint of excessive daytime sleepiness. Subsequent sleep laboratory evaluation revealed that each patient had concurrent obstructive sleep apnea. In each patient, endoscopic examination of the upper airway revealed that on inspiration, the soft tissue of the posterior and lateral hypopharynx invaginated into the laryngeal vestibule before any posterior movement of the tongue. Neither enlargement of the tongue nor in movement in relation to respiration appeared to be the primary factors in the etiology of the upper airway obstruction. After tracheostomy, both the obstructive sleep apnea and excessive daytime sleepiness were eliminated. Our case reports indicate that the treatment and prognosis of patients with acromegaly are affected when sleep apnea is concurrently diagnosed. When a patient is suspected of being acromegalic and also complains of excessive daytime sleepiness, obtaining a through sleep history from the patient as well as from the bed partner is essential. If sleep apnea is then diagnosed, a tracheostomy should be considered an initial and continuing part of the overall treatment plan.

(PDF emailed within 0-6 h: $19.90)

Accession: 005359266

Download citation: RISBibTeXText

PMID: 7076804

DOI: 10.1210/jcem-55-1-18

Related references

Correlation between severity of endoscopic findings and apnea-hypopnea index in patients with gastroesophageal reflux disease and obstructive sleep apnea. World Journal of Gastroenterology 11(6): 839-841, 2005

MRI findings in the hypopharynx and the larynx of a patient with acromegaly associated with severe obstructive sleep apnea syndrome. Endocrine Journal 46 Suppl: S105-S108, 2002

Abnormal orbicularis oculi reflex response in sleep apnea secondary to acromegaly. Evidence of pontomedullary dysfunction in sleep apnea syndrome. Israel Journal of Medical Sciences 24(2): 96-100, 1988

Endoscopic findings in sleep apnea syndrome. Journal of Otolaryngology 8(6): 487-493, 1979

Endoscopic findings in children with obstructive sleep apnea: effects of age and hypotonia. Pediatric Pulmonology 40(3): 205-210, 2005

Assessment of the awareness and management of sleep apnea syndrome in acromegaly. The COM.E.TA (Comorbidities Evaluation and Treatment in Acromegaly) Italian Study Group. Journal of Endocrinological Investigation 34(1): 60-64, 2011

Comparison of the cephalometric posterior airway analysis with endoscopic tongue base hypertrophy findings in patients with obstructive sleep apnea syndrome. Kulak Burun Bogaz Ihtisas Dergisi 21(2): 80-85, 2011

Sleep apnea in acromegaly. Annals of Internal Medicine 115(7): 527-532, 1991

Acromegaly and sleep apnea. Archivos de Bronconeumologia 40(8): 355-359, 2004

Sleep apnea in active acromegaly. Archives of Internal Medicine 145(5): 865-866, 1985

Acromegaly and sleep apnea syndrome. Annales D'endocrinologie 42(3): 205-232, 1981

Acromegaly with the sleep apnea syndrome. Acta Medica Portuguesa 10(12): 955-959, 1998

Ask the doctors. I have always had a snoring problem and recently underwent a sleep test at the insistence of my wife. I was diagnosed as having sleep apnea. We have read about the connection between sleep apnea and heart disease, and now we are both concerned. Will treating my sleep apnea reduce my heart risk?. Harvard Heart Letter 23(5): 2-2, 2013

Obstructive sleep apnea in epilepsy patients: the Sleep Apnea scale of the Sleep Disorders Questionnaire (SA-SDQ) is a useful screening instrument for obstructive sleep apnea in a disease-specific population. Sleep Medicine 4(6): 517-521, 2003

Acromegaly and sleep apnea: cephalometric evaluations. Annales D'endocrinologie 72(3): 211-217, 2011