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Endoscopic follow up of protruded type of borderline atypical epithelial lesions



Endoscopic follow up of protruded type of borderline atypical epithelial lesions



Stomach & Intestine (Tokyo) 17(4): 397-405



While studying 97 lesions of atypical epithelial change [in the stomach] by endoscopic follow-up with serial biopsy for > 1 yr (maximum 11 yr and 7 mo., average 3 yr and 11 mo.), the macroscopic and histological features were analyzed and discussed. Macroscopic growth of the lesion was noted in 11, cases regressed lesions were found in 2 cases, and the remaining 84 cases showed no change. Histological progression of the atypism was shown in 2 cases which were finally diagnosed as Group V by biopsy. The growth of the enlarged lesions classified into the following 5 patterns: partial growth of the lesion; diffuse growth of thw whole lesion; nodular formation besides the atypical lesion; growing lesion with central depression; and a mixed pattern. The above growth patterns were completely different from that of a hyperplastic polyp or an early protruded gastric carcinoma and it was specific for the atypical epithelial lesions. Among the 11 lesions 5 were operated on, 2 were polypectomized and 4 were endoscopically followed, of which only 2 showed any progression of the atypism. Although macroscopic growth is not the absolute indicator for malignant change, it suggests that the growing lesion may become a malignancy. Therefore, special attention should be paid to their follow-up.

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Accession: 005359284

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