EurekaMag.com logo
+ Site Statistics
References:
53,869,633
Abstracts:
29,686,251
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Endoscopic manometry of pancreatic and biliary sphincter zones in man. Basal results in healthy volunteers



Endoscopic manometry of pancreatic and biliary sphincter zones in man. Basal results in healthy volunteers



Digestive Diseases and Sciences 26(1): 7-15



An endoscopic manometric technique was applied to the study of intraductal biliary and pancreatic pressures and sphincter activity in normal subjects. A perfused system using a modified endoscopic retrograde cholangiopancreatography catheter was tested and found to provide reliable ductal and phasic recordings. Twenty-five healthy volunteers, aged 19-37, underwent endoscopic manometry under diazepam sedation. Distinct zones of high-pressure phasic activity were identified on pull-through from the pancreatic duct and common bile duct at mean distances of 4.5 and 5.0 mm, respectively, from the papillary orifice with frequencies of 7.0 +/- 1.8 (mean +/- SD) and 5.6 +/- 2.4 waves/min, respectively. These were considered to represent separate pancreatic duct and bile duct sphincters. Peak pancreatic duct sphincter pressure (47.6 +/- 8.2 mm Hg) and bile duct sphincter pressure (57.2 +/- 10.7 mm Hg) were similar. Pancreatic duct pressure was 11.4 +/- 3.0 mm Hg and common bile duct pressure was 3.0 +/- 2.5 mm Hg. Values were adjusted to duodenal pressure as zero reference. The ductal and sphincteric pressures reported in this study provide a basis for the assessment of physiological, pharmacological, pathophysiological, and surgical effects on this area.

(PDF emailed within 1 workday: $29.90)

Accession: 005359372

Download citation: RISBibTeXText

PMID: 7460708



Related references

Endoscopic manometry of biliary and pancreatic sphincters findings in biliary and pancreatic disease and after sphincter surgery. American Journal of Gastroenterology 72(3): 333, 1979

Endoscopic sphincter of Oddi manometry in healthy volunteers. Scandinavian Journal of Gastroenterology 22(2): 243-249, 1987

Endoscopic sphincter of oddi manometry abnormal findings in healthy volunteers. Gastroenterology 102(4 PART 2): A334, 1992

Biliary manometry is a low yield investigation in patients with recurrent biliary pain after endoscopic biliary sphincterotomy , but recurrent pancreatitis in this population may reflect previously undiagnosed pancreatic sphincter hypertension. Digestive Disease Week Abstracts & Itinerary Planner : Abstract No T1556, 2003

Endoscopic manometry of the sphincter of Oddi and the pancreatic and biliary ducts in patients with chronic pancreatitis. Scandinavian Journal of Gastroenterology 29(2): 188-192, 1994

Endoscopic pancreatic and biliary manometry in pancreatic, biliary, and papillary disease, and after endoscopic sphincterotomy and surgical sphincteroplasty. Gut 25(11): 1247-1254, 1984

Sphincter of oddi manometry: is it necessary to measure both biliary and pancreatic sphincter pressures?. Gastrointestinal Endoscopy 52(2): 183-186, 2000

Frequency of abnormal pancreatic and biliary sphincter manometry compared with clinical suspicion of sphincter of Oddi dysfunction. Gastrointestinal Endoscopy 50(5): 637-641, 1999

Pancreas divisum and its association with choledochal sphincter stenosis. Diagnosis by endoscopic retrograde cholangiopancreatography and endoscopic biliary manometry. American Journal of Surgery 147(3): 367-371, 1984

Sphincter of oddi manometry in 50 healthy volunteers. American Journal of Gastroenterology 83(9): 1069, 1988

Sphincter of Oddi manometry in healthy volunteers. Digestive Diseases and Sciences 35(1): 38-46, 1990

Endoscopic pancreatic and biliary manometry in health and in pancreatic biliary and papillary disease. Gastroenterology 78(5 PART 2): 1148, 1980

Endoscopic sphincter of oddi manometry in biliary dys kinesia. Langenbecks Archiv fuer Chirurgie 361: 135-138, 1983

Endoscopic manometry of the porcine pancreatic sphincter. Gastroenterology 118(4 Suppl 2 Part 1): A201, April, 2000

Quantitative hepatobiliary scintigraphy and endoscopic sphincter of Oddi manometry in patients with suspected sphincter of Oddi dysfunction: assessment of flow-pressure relationship in the biliary tract. European Journal of Gastroenterology & Hepatology 12(7): 777-786, 2000