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Endoscopic resection of early gastric cancer following locally injected hypertonic saline epinephrine



Endoscopic resection of early gastric cancer following locally injected hypertonic saline epinephrine



Stomach & Intestine (Tokyo) 23(4): 399-409



We have developed a new method of endoscopic resection of early gastric carcinomas and other tumors. Features of this new method are summarized as follows. 1. In order to prevent bleeding after endoscopic resection of tumors, local injection of hypertonic saline-epinephrine (HSE) solution was applied to the lesions. Depressed lesions like IIc type early gastric carcinomas were artificially made protruding by locally injecting HSE solution. 2. Double-fiberscopic method was employed. 3. Prior to the resection, high frequency current snare was made, followed by incision of the mucosa along this marking. This procedure made it possible to resect extensive area with precision. 4. Because of minimal tissue damage, resected materials were better suited for pathological study. Endoscopic resection in this way was performed in total of 113 cases of early gastric carcinoma. Curative resection was made in 103 cases (91.2%). The rest of the cases ultimately underwent surgical resection because of non-curative nature of endoscopic resection. Five-year survival rate in the former 103 cases was 85.2%. Endoscopic resection by this method we developed seems to be excellent in treating early gastric carcinoma with no lymph node metastasis, especially in patients at high surgical risk.

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Accession: 005359494

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