EurekaMag.com logo
+ Site Statistics
References:
53,869,633
Abstracts:
29,686,251
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Endoscopic studies of intestinal metaplasia of the stomach



Endoscopic studies of intestinal metaplasia of the stomach



Journal of Kyoto Prefectural University of Medicine 91(3): 185-202



With the development of magnifying fiberscope and the methylene blue (MB) staining method, intestinal metaplasia in the [human] gastric mucosa could be diagnosed by endoscopic examination. Findings were confirmed by histological examination of biopsy specimens under endoscopic direct vision. The occurrence of, evolution of and relation to various gastro-duodenal diseases of intestinal metaplasia were investigated. The frequency of intestinal metaplasia was greatly increased in patients > 40 yr old, and the MB staining area tended to spread with aging. Intestinal metaplasia was prevalent and severe in stomachs with gastric cancer and gastric polyp but was slight and localized in gastric erosion, gastritis erosiva and duodenal ulcer. The MB staining type was classified as depressed, flat or granular types. Most depressed types were seen in the younger generation in localized intestinalized mucosa of the stomach and in stomachs with gastric erosion, gastritis erosiva and duodenal ulcer. Granular type was seen in the elder generation with extensive intestinalized mucosa of the stomach, gastric cancer and gastric polyp. Flat type was seen with the same frequency in various ages and with various diseases. Follow-up observations using the MB staining method proved that the staining type developed from depressed type to flat type and from flat type to granular type. Some intestinal metaplasia occurred in regenerating mucosa of gastric erosion. The early stage of intestinal metaplasia rarely disappeared. Differentiated adenocarcinoma of early gastric cancer accompanied extensive intestinal metaplasia and was surrounded by the intestinalized mucosa. There was a close correlation between differentiated adenocarcinoma and intestinal metaplasia of the stomach.

(PDF emailed within 1 workday: $29.90)

Accession: 005359625

Download citation: RISBibTeXText



Related references

Intestinal metaplasia of the stomach. Frequency in a study of endoscopic biopsies. Acta Gastroenterologica Latinoamericana 15(3): 149-156, 1985

Endoscopic diagnosis of early cancer and intestinal metaplasia of the stomach by dyeing. International Surgery 58(9): 639-642, 1973

Endoscopic diagnosis of intestinal metaplasia of stomach--accuracy judged by histology. Hepato-Gastroenterology 46(25): 162-166, 1999

Endoscopic diagnosis of intestinal metaplasia of the stomach and its evaluation as a precancerous lesion. Frontiers of Gastrointestinal Research 5: 140-148, 1979

Methylene blue staining for the endoscopic diagnosis of intestinal metaplasia in the stomach. Gastroenterology 114(4 PART 2): A605, April 15, 1998

Endoscopic dyeing method for diagnosis of early cancer and intestinal metaplasia of the stomach. Endoscopy 5(3): 124-129, 1973

Helicobacter pylori is associated with intestinal metaplasia in the proximal and distal stomach but not with intestinal metaplasia in Barretts esophagus. Gastroenterology 114(4 PART 2): A135, April 15, 1998

Distribution of marker enzymes and mucin in intestinal metaplasia in human stomach and relation of complete and incomplete types of intestinal metaplasia to minute gastric carcinomas. Journal of the National Cancer Institute 65(2): 231-240, 1980

Histopathogenesis of intestinal metaplasia--minute lesions of intestinal metaplasia in the ulcer-bearing stomach. Gan No Rinsho. Japan Journal of Cancer Clinics 32(9): 971-976, 1986

Vital staining of the stomach for diagnosis of intestinal metaplasia: correlation of endoscopic, histologic and ultrastructural findings (proceedings). Zeitschrift für Gastroenterologie 16(11): 694-695, 1978

Enzymological studies of gastro intestinal mucosa intestinal metaplasia of rat stomach abstract methyl cholanthrene carcino. Gastroenterologia Japonica 3(1): 447-448, 1968

Comparison of clinical, endoscopic and functional findings in patients with intestinal metaplasia at the cardia, carditis and short-segment columnar epithelium of the distal esophagus with and without intestinal metaplasia. Diseases of the Esophagus 13(1): 61-68, 2000

Intestinal metaplasia of Barretts esophagus and its relation to intestinal metaplasia elsewhere in the stomach. Gastroenterology 112(4 SUPPL ): A572, 1997

Lectin histochemical studies of intestinal metaplasia in the stomach. Acta Histochemica et Cytochemica 19(3): 394, 1986