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Endothelial cell markers in vascular neoplasms an immunohistochemical study comparing factor vii related antigen blood group specific antigens 6 ketoprostaglandin f 1 alpha and ulex europaeus 1 lectin



Endothelial cell markers in vascular neoplasms an immunohistochemical study comparing factor vii related antigen blood group specific antigens 6 ketoprostaglandin f 1 alpha and ulex europaeus 1 lectin



Journal of Pathology 149(2): 89-96



Markers for endothelial cells including Ulex europaeus 1 lectin, blood group A, B, and H, and the prostaglandin metabolite 6-keto-PGF1 alpha were evaluated in paraffin sections from formalin-fixed benign and malignant vascular neoplasms using a variety of immunohistochemical techniques, and results compared with staining for factor VIII-related antigen. Staining for Ulex appeared more sensitive than factor VIII-related antigen in identifying poorly differentiated neoplasms including haemangiosarcomas and spindle cell proliferations in Kaposi's sarcoma. Staining for blood group related antigens correlated with blood group in all cases. Ulex europaeus 1 lectin was the only marker for endothelial cells in lymphangiomas.

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Accession: 005359923

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