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Epidemiological and clinical aspects of chronic asymptomatic hepatitis b virus infections in some population groups of gdansk poland agglomeration


, : Epidemiological and clinical aspects of chronic asymptomatic hepatitis b virus infections in some population groups of gdansk poland agglomeration. Annales Academiae Medicae Gedanensis 16: 79-94

In the years 1980-1981 some epidemiologic studies were conducted to evaluate for the indication of the frequency of occurrence asymptomatic HBV infections in some population groups of Gdansk agglomeration: school children, youth, students and adults, 4595 persons (age between 5-100) were examined. 90 persons (= 2% of the examined persons) were found, by immunoelectrophoresis, to have serological markers of either present (HBsAg) or past (anti-HBs) HBV infection. HBV infection was higher in men. The frequency of occurrence of antigenemia HBs was significantly higher in the group of school children (2,6%), than in the group of youth (0,6%) and students (1,6%). The highest prevalence (5,1%) was observed in patients with tuberculosis pulmonum (comparative group) and it increased in accordance with the duration of the anti-tuberculosis treatment. Only 8.4% of persons with HBV infection had past history of symptomatic hepatitis. In 70% of persons with HBV infection, the liver was enlarged, in 40%.sbd.abnormalities of liver function were observed on biochemical examinations. In 48% of persons, subjective complaints were present. Morphological examinations of liver biopsy specimens were performed in 38 HBV infected persons and 60% of them were recognized as real HBV carriers, in remaining 40%.sbd.different forms of acute and chronic hepatitis, including cirrhosis development, were recognized.

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