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Epidemiological and clinical studies of 16 cases with acute hepatitis type a in our clinic from february to may in 1983


, : Epidemiological and clinical studies of 16 cases with acute hepatitis type a in our clinic from february to may in 1983. Journal of the Iwate Medical Association 39(5): 663-674

From February to May in 1983, we experienced 16 cases of acute hepatitis type A in our clinic. All cases were diagnosed by detection of IgM class anti-HA using a radioimmunoassay kit (HAVABM). The male to female ratio of patients was 1:1.7. The average age was 32.6 .+-. 12.1 (Mean .+-. SD) years, ranging from 6 to 58 years of age, and 62.4% of the patients were between 20 to 39 years old. Twelve out of 15 patients (80%) had the history of eating raw fishes and shellfishes within 2 months before the onset. We suspected that raw fish and shellfish were important as being the infectious vehicle. Intrafamilial infection was observed in 6 family members of 3 pedigrees. Three of the members, who worked in the same office, seemed to be infected in turn. Patients had various symptoms such as anorexia, general fatigue and high fever. Atypical lymphocytes were found in 10 out of 15 cases (67%). The levels of thymol turbidity and immunoglobulin M were elevated. Neither the fulminant form nor a prolonged case were found in our observations.

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