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Epidemiological and immunobiological evaluation of prophylactic immunization schedules


, : Epidemiological and immunobiological evaluation of prophylactic immunization schedules. Zhurnal Mikrobiologii Epidemiologii i Immunobiologii (3): 29-33

The epidemiological and immunological evaluation of two immunization schedules approved by the Orders of the USSR Ministry of Health No. 322 of April 24, 1973, and No. 50 of January 14, 1980, has been made on the basis of the results obtained in the Brest region of the Byelorussian SSR and in the Turkmen SSR. According to these results, the use of the schedule approved by Order No. 50 has made it possible to increase the groups of children receiving correct and timely immunization with measles vaccine by 8.3% and 28.8% and with adsorbed DPT vaccine by 17.2% and 5.5% in the Brest region of the Byelorussian SSR and in the Turkmen SSR respectively. Considerable groups of children have been found to be immunized with deviations from the approved schedules with respect to the scheme and time of immunization: 62.1% and 44.5% in the Brest region, 81.3% and 80.5% in the Turkmen SSR (during the periods of the implementation of Orders No. 322 and No. 50 respectively). Acute respiratory viral infections, bronchitis and pneumonia have proved to be the main reasons for medical exemption from immunization in both republics, these diseases constituting 61.6-71.1% of all medical contraindications. The negative influence of earlier infectious diseases on the level of postvaccinal immunity has been shown.

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