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Epidemiological aspects of peptic ulcer in aragon spain


, : Epidemiological aspects of peptic ulcer in aragon spain. Revista Espanola de las Enfermedades del Aparato Digestivo 72(3): 221-226

An epidemiological study was made in 2000 individuals from the geographical region of Aragon (Spain), 1005 of whom suffered peptice ulcer diagnosed by fibroendoscopy. An analysis was made of the characteristics of this sample in relation to age, sex, ulcer location and complications. Likewise, the author studied environmental factors with possible pathogenic implications, like profession or toxin consumption: tobacco and alcohol. Ulcer location: duodenal: 34.8%, gastric 13.2%, and duodenal + gastric: 2.2%. The duodenal: gastric ulcer ratio was 3.6/1 for men and 1.1/1 for women. The mean age of women with duodenal ulcer was older than for men. Upper gastrointestinal hemorrhage was the most frequent complication in both sexes. Men showed a greater tendency to perforation, pyloric stenosis and operation motivated by failure of medical treatment. Gastric ulcers were complicated more often than duodenal ulcers. Construction workers showed the highest prevalence of peptic ulcer and 68% of professional drivers with peptic ulcer presented upper gastrointestinal hemorrhage, as compared with 30.7% for construction workers. Of the ulcer cases, 58.8% were smokers as compared to 44.4% of the control group (p < 0.001). Alcohol consumption showed no relation with a higher incidence of peptic ulcer or complications.

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