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Epidemiological characterization of untypable vi strains of salmonella typhi

, : Epidemiological characterization of untypable vi strains of salmonella typhi. Indian Journal of Medical Research 73(JUNE): 821-831

A complementary phage typing scheme for epidemiological characterization of untypable Vi-strains (UVS) of S. typhi was described. The lytic patterns obtained with a battery of 20 somatic phages were represented by a mnemonic based on a coding system. This scheme was used along with the biochemical typing for the differentiation of 568 UVS isolated from India and Burma during the years 1976-78. The strains of a particular lytic pattern and biotype were predominant is in a particular region. There was no difference between the lytic patterns of a few UVS and their corresponding Vi-negative variants which indicated that the Vi antigen did not become a barrier for the adsorption of these phages to the cell wall of S. typhi. The stability and reproducibility of the lytic patterns of UVS isolated from a particular patient showed that the scheme can be applied to the epidemiological situations.

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