+ Site Statistics
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Epidemiological factors related to the malignant neoplasms in ataxia telangi ectasia families

, : Epidemiological factors related to the malignant neoplasms in ataxia telangi ectasia families. Journal of Chronic Diseases 31(9-10): 625-634

In response to the demonstration of an increased risk of death from specific neoplasms among the blood relatives of patients homozygous for ataxia-telangiectasia (A-T) a review of the epidemiology of selected neoplasms and its application to the A-T relatives' mortality experience is presented. Demographic, social and medical factors associated with cancers of the gall bladder and bile ducts, ovary and stomach do not explain the increased number or the unusually early age of onset of these malignancies observed among the A-T family members. Although this analysis is limited in scope and reflects a univariate approach to the etiology of the various cancers considered, it supports a genetic basis for an increased susceptibility to malignant neoplasms among A-T heterozygotes.

(PDF 0-2 workdays service)

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 005375260

PMID: 744793

PDF Full Text: Submit

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

Pössl, J.; von Zerssen, D., 1990: The premorbid development of patients with various forms of psychoses. Der Nervenarzt 61(9): 541-549

Ramirez Valderrama, A.; Ruiz, D.; Malik, M.; Tiszenkel, H., 2014: Femoral hernia sac laparoscopy: a case report. We present the case of a 64-year-old female with an incarcerated right femoral hernia, associated with a small bowel obstruction that was successfully treated with an open femoral hernia repair with plug. At the same time we performed a hernia sac...

Anonymous, 2013: Dpp induction of vn initiates wing development. The acquisition of flight contributed to the success of insects and winged forms are present in most orders. Key to understanding the origin of wings will be knowledge of the earliest postembryonic events promoting wing outgrowth. The Drosophila m...

Mathur, D. S., 1964: Lethal effects of BHC on certain fish. BHC (benzene hexachloride) in concentrations of 10% and 20% proved to be lethal to the following species of fish: Ophicephalus punctatus, Heteropneustes fossilis and Trichogaster fasciatus. Young fish were least resistant.

Ali, M.; Afzal, M., 1987: A potent inhibitor of thrombin stimulated platelet thromboxane formation from unprocessed tea. A ninhydrin positive compound (L2) from commercially available unfermented dry green tea (Thea sinesis) leaves is found to be a potent inhibitor of thrombin-stimulated thromboxane formation in rabbit whole blood. Its potency is compared with caffe...

Tong, Q.; Ouedraogo, R.; Kirchgessner, A.L., 2002: Localization and function of group III metabotropic glutamate receptors in rat pancreatic islets. Pancreatic islets contain ionotropic glutamate receptors that can modulate hormone secretion. The purpose of this study was to determine whether islets express functional group III metabotropic glutamate (mGlu) receptors. RT-PCR analysis showed...

Constantin, A., 2012: Nonlinear water waves. This introduction to the issue provides a review of some recent developments in the study of water waves. The content and contributions of the papers that make up this Theme Issue are also discussed.

Wang, S.; Zhao, Y.; Leiby, M.A.; Zhu, J., 2009: Studying human telomerase gene transcription by a chromatinized reporter generated by recombinase-mediated targeting of a bacterial artificial chromosome. The endogenous human telomerase reverse transcriptase (hTERT) gene is repressed in somatic cells. To study the mechanisms of its repression, we developed a strategy of retrovirus-directed Cre recombinase-mediated BAC targeting, or RMBT, to generat...

Epstein, G.S.; Hillman, A.L.; Weiss, A., 2002: Creating illegal immigrants. This paper studies the prospects of implementation of guest-worker programs by governments that are based on an intended temporary presence of foreign workers. The purpose of guest- worker programs is to alleviate sector-specified labor shorta...

Fujimoto, S.; Kodama, M.; Suga, H.; Namikawa, T.; Namikawa, T., 1980: Measurement of antithyroid antibodies using the dried blood spot. Horumon to Rinsho. Clinical Endocrinology 28(10): 1201-1203