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Epidemiological markers of Klebsiellae infecting hospital patients

East African Medical Journal 63(1): 22-28
Epidemiological markers of Klebsiellae infecting hospital patients
Strains of clinical isolates of Klebsiellae from both inpatients and outpatients were examined for biotypes, bacteriocine (Klebecin) types, serotypes and sensitivity to various routinely used antibiotics. In-patients mainly had chronic illnesses including carcinoma of the bileduct, liver colon and bronchus; diabetes mellitus, systemic lupus erythematosus, Guillain Barre' syndrome, or were undergoing renal transplant. The out-patients mainly had urinary tract infection or chronic bronchitis. The factors contributing to colonisation of infection by Klebsiella spp. were found to include previous broad-spectrum antibiotic therapy, age, frequency and duration of hospital admissions, and severity of underlying disease. Biotyping was found to be inadequate for identification. Antibiograms and Klebecin typing were found to be useful and it was further observed that Klebecin typing approximated the accuracy of serotyping. The two techniques of antibiogram and Klebecin typing could be developed for use by laboratories without the capacity to perform serotyping.

Accession: 005375336

PMID: 3519180

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