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Epidemiological models for heterogeneous populations proportionate mixing parameter estimation and immunization programs


Mathematical Biosciences 84(1): 85-118
Epidemiological models for heterogeneous populations proportionate mixing parameter estimation and immunization programs
Deterministic models are presented for epidemics which occur quickly and for long-term endemic diseases where births and deaths must be considered. Contact-rate matrices are formulated in terms of activity levels and subpopulation sizes by using a proportionate-mixing assumption. Methods are presented for estimating epidemic and endemic parameters in both homogeneous and heterogeneous populations. Other authors' approaches to contact-rate matrices and spatial heterogeneity are described. Three immunization programs are analyzed for a model of a spatially heterogeneous population and are compared in a "city and villages" example.

Accession: 005375339

DOI: 10.1016/0025-5564(87)90044-7

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