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Epidemiological studies of chlordane for termite prevention part 1. chlordane residues of houses treated for termites and results of blood tests of pest control operators






Okayama Igakkai Zasshi 97(3-4): 315-326

Epidemiological studies of chlordane for termite prevention part 1. chlordane residues of houses treated for termites and results of blood tests of pest control operators

Chlordane is widely used as an anti-termite pesticide for wooden houses. Pest control operators as well as the residents of chlordane treated houses might become sick through the exposure to the chemical. The chlordane concentration in the air and soil after the treatment was examined. The chlordane concentration in the blood of pest control operators was also examined. A 40% emulsion of chlordane was used together with a 2% petroleum emulsion as a sprinkling pesticide. Its constituents as determined by GC-ECD were in the descending order of trans-chlordane, trans-nonachlor, cis-chlordane, .gamma.-chlordene, heptachlor and cis-nonachlor. The chlordane concentration in the air was the highest immediately after the treatment, and decreased gradually with the lapse of time. Heptachlor was the largest, and cis-nonachlor the smallest constituent of chlordane detected in the air. On the contrary, cis-nonachlor was the largest, and heptachlor the smallest constituent in the soil. This suggests that the exposure dose of heptachlor may be extreme. Heptachlorepoxide and oxychlordane as metabolites, and trans-nonachlor and cis-nonachlor were detected in the blood of pest control operators. The C.P.K. value increased in their blood.


Accession: 005375403



Related references

Noguchi, N., 1985: Epidemiological studies of chlordane for termite prevention part 2. metabolism of chlordane in exposed rats. I exposed rats to chlordane (industrial product) and measured the concentration of chlordane in various tissues of rats over time. Exposure to chlordane for 3.5 hours approximated the exposure to chlordane in a house a hundred days after treatment...

Noguchi, N., 1985: Epidemiological studies of chlordane for termite prevention part 3. effect of chlordane on oxidative phosphorylation in rat liver mitochondria. In order to clarify the cytotoxicity of chlordane (industrial product as insecticide), the effect on oxidative phosphorylation in rat liver mitochondria was studied. The respiration rate, RCI and ADP/O ratio were inhibited by chlordane related com...

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