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Epidemiological study of a multi resistant enterobacter cloacae agent of iatrogenic infections in a surgical unit


Zentralblatt fuer Veterinaermedizin Reihe B 31(1): 73-77
Epidemiological study of a multi resistant enterobacter cloacae agent of iatrogenic infections in a surgical unit
E. cloacae caused severe wound infections in 4 dogs and a cat, 5-7 days post-operation. In an environmental investigation, E. cloacae could also be isolated from a solution of Nebacetine used for prevention of bacterial infection. The observed E. cloacae strains were biochemically identical and harbored a conjugative plasmid for resistance to ampicillin, chloramphenicol, kanamycin, neomycin, streptomycin, sulfonamide, tetracycline and trimethoprim. The cleavage of the resistance plasmids with EcoRI generated an identical restriction pattern in 4 cases. Two plasmids lacked the 4.7 megadalton (Mdal) fragment of the basic pattern. Instead there was an additional DNA-fragment of 7.2 Mdal. The facts suggest a common origin of the E. cloacae strains and an iatrogenic infection of the affected animals.


Accession: 005375540



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