+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Epidemiological study of chronic hepatitis in relation to hepatitis b virus infections

Annali Sclavo 19(5): 925-934

Epidemiological study of chronic hepatitis in relation to hepatitis b virus infections

To evaluate the role of hepatitis B virus (HBV) in the etiology of chronic liver diseases, paired sera of 143 patients with biopsy-documented chronic hepatitis were tested for HBsAg [hepatitis B surface antigen] and anti-HBs [antibody to HBsAg] by radioimmunoassay. HBsAg was detected in 67.3% of patients with a preceding verified episode of acute hepatitis, and in 26.7% of patients with a cryptogenic form of chronic hepatitis. HBsAg was not found in any patients with alcoholic chronic hepatitis and in only 2 of 18 patients with other forms of chronic liver disease. No significant difference in the incidence of anti-HBs was observed in all groups of patients. The results confirm the higher prevalence of HBV infection in the etiology of chronic persistent and aggressive hepatitis and indicate that this prevalence may be observed especially in middle and south Italy. The presence of HBsAg in the serum of 37.2% of patients with cirrhosis compared with 9% of reported cases in North Italy suggests that HBV plays an important role in the etiology of cirrhosis of the liver in middle and south Italy.

(PDF 0-2 workdays service: $29.90)

Accession: 005375551

Related references

Chronic hepatitis in patients with active hepatitis B virus and hepatitis C virus combined infections: a histological study. American Journal of Gastroenterology 90(6): 955-958, 1995

A comparative epidemiological study of hepatitis B and hepatitis D virus infections in Yanomami and Piaroa Amerindians of Amazonas State, Venezuela. Tropical Medicine & International Health 15(8): 924-933, 2010

Epidemiological and clinical burden of chronic hepatitis B virus/hepatitis C virus infection. A multicenter Italian study. Journal of Hepatology 39(6): 1036-1041, 2003

Hepatitis C virus genotypes: epidemiological and clinical associations. Benelux Study Group on Treatment of Chronic Hepatitis C. Liver 18(1): 32-38, 1998

Correlation between hepatic hepatitis B core antigen and serum hepatitis B virus-DNA levels in patients with chronic hepatitis B virus infections in Taiwan. Archives of Pathology & Laboratory Medicine 111(2): 181-184, 1987

Intrahepatic expression of pre-S1 and pre-S2 antigens in chronic hepatitis B virus infection in relation to hepatitis B virus replication and hepatitis delta virus superinfection. Gut 33(11): 1544-1548, 1992

Interactions between human immunodeficiency virus-1, hepatitis delta virus and hepatitis B virus infections in 260 chronic carriers of hepatitis B virus. Hepatology 15(4): 578-583, 1992

Epidemiologic study of chronic hepatitis in relation to heptatis B virus infections. Annali Sclavo; Rivista di Microbiologia E di Immunologia 19(5): 925-934, 1977

Epidemiological study of hepatitis B virus genotypes, core promoter and precore mutations of chronic hepatitis B infection in Hong Kong. Journal of Hepatology 41(1): 119-125, 2004

Chronic posttransfusion non-A, non-B hepatitis and autoimmune chronic active hepatitis-aspects on treatment, prognosis and relation to hepatitis C virus. Scandinavian Journal of Infectious Diseases. Supplementum 79: 1-48, 1991