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Epidemiological study on cancer of the large intestine in japan 1. fundamental analysis from mortality of the large intestine in japan

, : Epidemiological study on cancer of the large intestine in japan 1. fundamental analysis from mortality of the large intestine in japan. Journal of the Japan Society of Coloproctology 36(6): 607-614

The age-adjusted death rates from large intestinal cancer from 1955-1980 were analyzed. The trend of an increase of cancer in the colon was greater than that in the rectum. The increase of colonic cancer was mainly due to the fact that the age-adjusted death rate from cancer of the sigmoid colon increased markedly. The female age-adjusted death rate for cancer of the cecum, appendix and ascending colon slightly surpassed the male rate, while the male age-adjusted death rate for cancer of the transverse and descending colon, the sigmoid colon and the rectum surpassed the female's. The closer to the anal region the large intestinal cancer was, the larger the sex ratio (male/female) became. With age, the age-specific death rates for rectal and colonic cancer increased. Etiological differences apparently exist among the segments of different large intestinal cancer. Application of analytical epidemiology to the study of cancer in each segment of the large intestine is recommended to determine the mechanism of cancer occurrence.

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